… We argue here that genomic guidance should be embedded in all drug development and
treatment … used medications in clinical practice. The success of pharmacogenomics in GWAS …

… impact on the clinical practice of medicine. Herein, we discuss the potential implications
of pharmacogenomics on the drug development process, including drug safety, productivity, …

… been incorporated into medical practise, despite the … use of pharmacogenomic testing
during drug development. The graph in Figure 1 shows the increase in pharmacogenomic clinical …

… pharmacogenomics into the clinical practice of medicine (Figure 1) . Together with educational
efforts to improve pharmacogenomics teaching in medical … of pharmacogenomic-guided …

… pharmacogenomic information will have a large impact on drug development and,
subsequently, clinical practice… the routine use of pharmacogenomic testing in clinical practice. A …

… drug development using pharmacogenomics as a tool and the diagnostic procedures all need
to be critically analysed. Pharmacogenomics … It is concerned with genetic effects on drugs …

… We propose a framework for the role of PGx in early-phase drug development and … in clinical
practice has been slow Citation[4,32,37,45–48]. PGx-driven clinical practice guidelines with …

… development and clinical practice. SNP arrays covering 5 million SNPs will soon become
a reality, and the cost for whole-genome sequencing is rapidly decreasing, with companies …

… clinical studies are necessary for development of clinical guidelines on PGDx. Therefore, we
examine relevant study designs and suggest where in drug development … drug development …

… drug development, pharmacogenetics could be applied to compound screening and identifying
potential side effects before entering full clinical … is a routine clinical practice in order to …