… Mesenchymal transformation confers cells with enhanced migratory ability and is consistent
… transformation of glioma cells results in a migratory phenotype, we evaluated U87 GBM cell …

… fusogenicity to the phenotypic changes observed in gliomas, we studied the interaction of
glioma cells with stroma. The stromal mesenchyme provoked in glioma cells contact-mediated …

… line (U343MGa 31 L) or on Ki-ras-transformed … blastoma cell line. Furthermore, we provide
evidence that the autocrinc PDGF pathway drives the transformed phenotype of the tumor cells…

… on transforming growth factor-a (TGF-a) released from glioma … Glioma cells can grow in two
different phenotypes, as adherent monolayer cells which represent differentiated glioma cells …

… (A) Primary microglial cultures were exposed to conditioned media from C6 glioma cells (GCM),
non-transformed astrocytes (ACM), or stimulated with 100 ng/mL LPS. Morphological …

… .23, 35 We studied the possibility to alter the transformed phenotype of U87MG glioblastoma
cells through the expression of the miR-302/367 cluster. For this purpose, we cloned a part …

… The occurrence of an aggressive glioma phenotype depends on EMT (epithelial-…
transformation), in which epithelial cells transform into mesenchymal cells by losing their cell-cell …

… to play a pivotal role in glioma cell invasion and … transformation of U87MG glioma cells.
Three-dimensional culture platforms elicit significantly different responses of U87MG glioma cells …

… “mesenchymal” phenotypes described in the … phenotype of initiating GBM was maintained
in derived sphere cultures and also as xenograft models, indicating that some glioma cells are …

… is decreased in human brain tumor cell lines. Transfection of the cx43 gene into human
glioblastoma cells reverses the transformed phenotype of these tumor cells. Furthermore, it is …