… This review has emphasized on involvement of Akt/Erk cascade in the neurodegeneration.
Akt … These support that ERK activation alone may not be predictive of the subsequent cellular …

… While mTORC1 relays signals following PI3K–AKT activation, the mTORC2 complex leads
to the complete AKT activation by phosphorylating AKT on serine 473. AKT phosphorylation …

… Activated ERK has many … activation of the Ras-Raf-MEK-ERK signaling pathway is important
in the pathogenesis of melanoma. Activation of the Ras-Raf-MEK-ERK signaling pathway in …

… role of PI3K/Akt pathway in the cardioprotection of IP, we also determined whether the PI3K/Akt
pathway … To evaluate Akt activity after myocardial ischemia, we assessed Akt activity and …

… study, ERK activation was not affected by the inhibitor of PI3K and also the Akt activation was
… 2A), indicating that ERK and Akt are activated by MEK and PI3K, respectively, and there is …

… PI3K and Akt for MEK-independent ERK activation, we transfected T47D cells either with
siRNA against Akt1, Akt2 (Akt … ), catalytic or regulatory subunits of PI3K or with negative control …

… In the present study, we investigated the activation of EGFR, PI3K/AKT, and Raf/MAPK/ERK
1/2 during ischemia or reperfusion of the brain using the middle cerebral artery occlusion …

… MEK by phosphorylation, and MEK phosphorylation promotes ERK 1 and 2 … activation
of the RAF/MEK/ERK signaling pathway. Similar to PI3K/AKT/mTOR, activation of RAF/MEK/ERK …

… We present data demonstrating that EV71 infection activates the PI3K/Akt and MAPK/ERK …
to induce either PI3K/Akt and/or MAPK/ERK upon infection resulting in activation of the host …

… and SFN through activation of FOXO transcription factors [24, 101]. … of PI3K/AKT and ERK
pathways activates FOXO transcription factors. SFN inhibited phosphorylation of AKT and ERK, …