Roles of PI3K/AKT/GSK3/mTOR pathway in cell signaling of mental illnesses
Y Kitagishi, M Kobayashi, K Kikuta… - Depression research …, 2012 - Wiley Online Library
… PI3K/AKT and GSK3 pathways may constitute an important signaling center in the subcellular
integration of the synaptic neurotransmission. The pathways … the PI3K/AKT/GSK3 pathways …
integration of the synaptic neurotransmission. The pathways … the PI3K/AKT/GSK3 pathways …
Roles of PI3K/AKT/GSK3 pathway involved in psychiatric illnesses
S Matsuda, Y Ikeda, M Murakami, Y Nakagawa, A Tsuji… - Diseases, 2019 - mdpi.com
… the PI3K/AKT/GSK3 pathway may organize an intracellular central network for the action of
the synaptic neuroplasticity. In addition, the pathways … of the PI3K/AKT/GSK3 pathways in cell …
the synaptic neuroplasticity. In addition, the pathways … of the PI3K/AKT/GSK3 pathways in cell …
Regulation of PI3K/Akt/GSK‐3 pathway by cannabinoids in the brain
A Ozaita, E Puighermanal… - Journal of …, 2007 - Wiley Online Library
… and identifying methods capable of diminishing the deleterious impact of GSK-3 in … of the
PI3K/Akt/GSK-3 pathway. We found a close regulation of Akt and GSK-3 phosphorylation by …
PI3K/Akt/GSK-3 pathway. We found a close regulation of Akt and GSK-3 phosphorylation by …
GSK3 and its interactions with the PI3K/AKT/mTOR signalling network
… Therefore, a major role of GSK3 can be viewed as an amplifier of the … GSK3 regulation
and function, and the functions of GSK3 as it integrates with signalling through the PI3K-AKT…
and function, and the functions of GSK3 as it integrates with signalling through the PI3K-AKT…
Interleukin‐10‐induced gene expression and suppressive function are selectively modulated by the PI3K‐Akt‐GSK3 pathway
TT Antoniv, LB Ivashkiv - Immunology, 2011 - Wiley Online Library
… (PI3K) -mediated signalling regulates inflammatory responses and can induce IL-10 production,
but a role for PI3K … the involvement of the PI3K-Akt-GSK3 signalling pathway in IL-10-…
but a role for PI3K … the involvement of the PI3K-Akt-GSK3 signalling pathway in IL-10-…
AKT/GSK3 signaling pathway and schizophrenia
ES Emamian - Frontiers in molecular neuroscience, 2012 - frontiersin.org
… signaling pathways in schizophrenia. In this review, we mainly focus on AKT/GSK3 signaling
pathway in … AKT is activated by PI3K, which itself is activated by several upstream signaling …
pathway in … AKT is activated by PI3K, which itself is activated by several upstream signaling …
Dietary regulation of PI3K/AKT/GSK-3β pathway in Alzheimer's disease
Y Kitagishi, A Nakanishi, Y Ogura… - Alzheimer's research & …, 2014 - Springer
… This pathway appears to be … the PI3K/AKT/GSK-3β pathways in cell signaling of neuronal
cells. We also review recent studies on the features of several diets and the signaling pathway …
cells. We also review recent studies on the features of several diets and the signaling pathway …
LY3023414 inhibits both osteogenesis and osteoclastogenesis through the PI3K/Akt/GSK3 signalling pathway
X Chen, W Chen, ZM Aung, W Han… - Bone & Joint …, 2021 - boneandjoint.org.uk
Aims LY3023414 is a novel oral phosphatidylinositol 3-kinase (PI3K)/mammalian target of
rapamycin (mTOR) dual inhibitor designed for advanced cancers, for which a phase II clinical …
rapamycin (mTOR) dual inhibitor designed for advanced cancers, for which a phase II clinical …
Inhibition of the PI3K/Akt/GSK3 pathway downstream of BCR/ABL, Jak2-V617F, or FLT3-ITD downregulates DNA damage-induced Chk1 activation as well as G2/M …
T Kurosu, T Nagao, N Wu, G Oshikawa, O Miura - PloS one, 2013 - journals.plos.org
… by inactivating GSK3 through the PI3K/Akt signaling pathway to … The PI3K inhibitor GD-0941
or the Akt inhibitor MK-2206 … GSK3 inhibitors, including LiCl and SB216763, restored the …
or the Akt inhibitor MK-2206 … GSK3 inhibitors, including LiCl and SB216763, restored the …
Insulin promotes mitochondrial respiration and survival through PI3K/AKT/GSK3 pathway in human embryonic stem cells
… PI3K/AKT activation and downstream GSK3 inhibition. We further show that insulin acts
through GSK3 … This study uncovers a critical role of the AKT/GSK3 pathway in the regulation of …
through GSK3 … This study uncovers a critical role of the AKT/GSK3 pathway in the regulation of …
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