Marine indole alkaloids: potential new drug leads for the control of depression and anxiety

AJ Kochanowska-Karamyan, MT Hamann - Chemical reviews, 2010 - ACS Publications
… In this review, we have discussed 46 natural indole alkaloids of marine origin and 87
synthetic molecules. The synthesis of monoindole alkaloids was in many cases inspired by the …

Indole alkaloids from plants as potential leads for antidepressant drugs: A mini review

HA Hamid, ANM Ramli, MM Yusoff - Frontiers in pharmacology, 2017 - frontiersin.org
indole alkaloids isolated with antidepressant activity. This review provides information on the
potential of natural indole alkaloids … metabolites as potential antidepressant drug leads from …

Indole alkaloids with potential anticancer activity

D Xu, Z Xu - Current topics in medicinal chemistry, 2020 - ingentaconnect.com
… Therefore, indole alkaloids occupy an important position in the … development of indole alkaloids
as potential anticancer agents, … Thus, the two indole alkaloids could serve as lead hits for …

The current scenario of naturally occurring indole alkaloids with anticancer potential

J Song, B Zhang, M Li, J Zhang - Fitoterapia, 2023 - Elsevier
… naturally occurring indole alkaloids have the potential to inhibit … Accordingly, naturally
occurring indole alkaloids exhibit … indole alkaloids play a pivotal role in providing lead hits/…

Natural indole‐containing alkaloids and their antibacterial activities

Y Liu, Y Cui, L Lu, Y Gong, W Han… - Archiv der …, 2020 - Wiley Online Library
… of indole-containing alkaloids with antibacterial potential, … Thus, this indole-containing
alkaloid could serve as a lead … Bisindole alkaloids, consisting of two monomeric indole alkaloid

Indole alkaloids from marine sources as potential leads against infectious diseases

PHB França, DP Barbosa, DL da Silva… - BioMed research …, 2014 - Wiley Online Library
… Therefore this review highlighted some marine indole alkaloids which may be considered
as potential starting points for the development of novel agents for the treatment of infectious …

Therapeutic potential of indole alkaloids in respiratory diseases: A comprehensive review

S Mitra, SR Prova, SA Sultana, R Das, F Nainu… - Phytomedicine, 2021 - Elsevier
… the in-depth therapeutic potential of indole alkaloids against various respiratory disorders. …
the therapeutic potential, this review also evaluates the toxicity of these alkaloids, which have …

[HTML][HTML] Advances in indole-containing alkaloids as potential anticancer agents by regulating autophagy

ML Luo, W Huang, HP Zhu, C Peng, Q Zhao… - Biomedicine & …, 2022 - Elsevier
… of indole alkaloids' effect on tumor cells and autophagy. Then, we focus on mechanisms by
which indole alkaloids … Therefore, these chemical entities can be used as lead compounds in …

Indole alkaloids of the Stigonematales (Cyanophyta): Chemical diversity, biosynthesis and biological activity

K Walton, JP Berry - Marine Drugs, 2016 - mdpi.com
Potential Source of Drug Leads Finally, in terms of the potential of these indole alkaloids
as leads to pharmaceutical, the literature is, in fact, rather limited. However, pharmacological …

Plant-based indole alkaloids: A comprehensive overview from a pharmacological perspective

F Omar, AM Tareq, AM Alqahtani, K Dhama… - Molecules, 2021 - mdpi.com
… is to summarize the pharmacological potential of indole alkaloids that have been derived …
, which may contribute to identifying new lead compounds. The study was performed by …