Metabolic inflammatory complex in sepsis: septic cachexia as a novel potential therapeutic target
M Kaneki - Shock, 2017 - journals.lww.com
… that septic cachexia may be a novel target disease state, which would help identify new
molecular targets to improve outcomes of septic … This possibility is discussed in light of new …
molecular targets to improve outcomes of septic … This possibility is discussed in light of new …
Microglia: a potential therapeutic target for sepsis-associated encephalopathy and sepsis-associated chronic pain
Y Li, L Yin, Z Fan, B Su, Y Chen, Y Ma… - Frontiers in …, 2020 - frontiersin.org
… Thus, exploring the roles of microglia in SAE and long-term cognitive impairment will deepen
our understanding of pathology of SAE and probably offer a potential therapeutic target for …
our understanding of pathology of SAE and probably offer a potential therapeutic target for …
The microcirculation as a therapeutic target in the treatment of sepsis and shock
VSK Edul, A Dubin, C Ince - Seminars in respiratory and critical …, 2011 - thieme-connect.com
… has provided the promise of identifying new therapeutic targets. Clinical research has
identified various conventional and new therapeutic approaches that are successful in modifying …
identified various conventional and new therapeutic approaches that are successful in modifying …
Cannabinoid receptor 2: a potential novel therapeutic target for sepsis?
Q He, F Xiao, Q Yuan, J Zhang, J Zhan… - Acta Clinica …, 2019 - Taylor & Francis
… This review discusses available data regarding the role of CB2R in sepsis and the possible
underlying mechanism. In summary, the accumulated evidence revealed that activating …
underlying mechanism. In summary, the accumulated evidence revealed that activating …
Long noncoding RNA: regulatory mechanisms and therapeutic potential in sepsis
W Wang, N Yang, R Wen, CF Liu… - … in cellular and infection …, 2021 - frontiersin.org
… treatment for sepsis, lncRNAs may be promising biomarkers and even targets for sepsis
therapies… the roles of lncRNAs in sepsis and sheds light on their use as potential biomarkers and …
therapies… the roles of lncRNAs in sepsis and sheds light on their use as potential biomarkers and …
Immune checkpoints: novel therapeutic targets to attenuate sepsis-induced immunosuppression
MA McBride, TK Patil, JK Bohannon… - Frontiers in …, 2021 - frontiersin.org
… approved therapy currently exists to treat sepsis (9). Therefore, there is a critical need to
advance our … of sepsis pathology and identify novel biological targets for the development of new …
advance our … of sepsis pathology and identify novel biological targets for the development of new …
[HTML][HTML] New paradigms in sepsis: from prevention to protection of failing microcirculation
J Hawiger, RA Veach, J Zienkiewicz - Journal of Thrombosis and …, 2015 - Elsevier
… in the first ‘golden hour’, including pre‐hospital settings, is the goal to avert widespread …
‐life (up to 29 h) 81 , further expands the potential of intracellular protein therapy for sepsis. …
‐life (up to 29 h) 81 , further expands the potential of intracellular protein therapy for sepsis. …
Therapeutic targets and signaling mechanisms of vitamin C activity against sepsis: a bioinformatics study
R Li, C Guo, Y Li, Z Qin, W Huang - Briefings in bioinformatics, 2021 - academic.oup.com
… approach to reveal predictive targets and therapeutic mechanisms underlying the action of
VC against sepsis. We hope that the predictive targets and therapeutic mechanisms may be …
VC against sepsis. We hope that the predictive targets and therapeutic mechanisms may be …
A new paradigm for the treatment of sepsis: is it time to consider combination therapy?
AS Cross, SM Opal - Annals of internal medicine, 2003 - acpjournals.org
… these patients susceptible to fatal infection. It is now time to test a new therapeutic paradigm
based on an improved understanding of the pathophysiology of the septic process and the …
based on an improved understanding of the pathophysiology of the septic process and the …
Fibrinolytic alterations in sepsis: biomarkers and future treatment targets
JB Larsen, AM Hvas - Seminars in Thrombosis and Hemostasis, 2021 - thieme-connect.com
… To assess current literature on potential markers for altered fibrinolysis in sepsis, we performed
a literature search in PubMed and Embase on February 01, 2020. Studies were included …
a literature search in PubMed and Embase on February 01, 2020. Studies were included …