… the crucial role that microcirculation plays in sepsis. If not corrected, … as an important target
in the pathogenesis of sepsis and its … diagnostic and therapeutic target for treatment in sepsis. …

… As the pathophysiologic events that take place during sepsis are being elucidated, new
molecules that target each step of those pathways are being tested. However, a lot of those …

… septic organism copes with this schism, and whether these insights can lead to new
therapeutic … during sepsis and the possible consequences, we could be paving the way to a …

… Neutrophils are therefore a logical target for the treatment and perhaps prevention of sepsis
by attenuation of their release and activity. The results of the HETRASE trial [101] suggested …

… sepsis. In this Perspective, we highlight the endothelial barrier as a new target for sepsis
therapeutics, examining three potential … Another potential therapeutic strategy for treating sepsis …

… has been disappointing, and the investigation of strategies aiming at re-balancing the
profound immune dysregulation during sepsis and septic shock seems to be a promising goal. …

… In this context, the present review describes the role of the efferent vagal transmission in
controlling inflammation during sepsis and highlights the pharmacologic targets that can be …

… leading to a new generation of drugs capable of treating not only sepsis but also chronic …
forms of sepsis. Attention has therefore turned to new drugs that directly target cytokines or the …

… These provide new potential targets for intervention in sepsis … knowledge on endotoxin
sensing in sepsis with special focus on … and discuss potential therapeutic approaches addressing …

… disease severity, prognosis, and potential future therapeutic targets in patients with sepsis
(34–36). Thus, to correlate symptoms with different phases of sepsis, it is important to survey …