… Globally, scientists are looking for therapeutic agents that can either cure or delay the onset
of diseases, laying more emphasis on natural extracts that possess the potential to serve as …

… a tremendous interest in discovering PLA 2 inhibitors as novel potential therapeutic agents.
… PLA 2 enzymes are potential new agents for the treatment of various inflammatory diseases. …

… 5D) series of compounds were synthesized as potential therapeutic agents for PD [111]. The
metal binding hydroxamic acid functional group is essential to provide neuroprotection in 6-…

… This review describes small molecule P2X7 antagonists that have first appeared in the
literature since 2009 and have potential therapeutic utility in the CNS, or for which new data have …

… of SARS and MERS, many efforts in vaccine and treatment strategy development are being
made vigorously. This review focuses on the potential therapeutic agents that have been …

HDAC2 inhibitors are members of a new class of agents that modulate the expression of genes
by causing an increase in histone acetylation, thereby regulating chromatin structure and …

Inhibitors of the Hsp90 molecular chaperone are showing considerable promise as
potential chemotherapeutic agents for cancer. Here, we describe the structure-based design, …

Cancer denotes a pathological manifestation that is characterized by hyperproliferation of
cells. It has anticipated that a better understanding of disease pathogenesis and the role of cell…

A wide variety of studies in vitro, in vivo, and in clinical trials have demonstrated that the
chelator currently used to treat iron overload disease, desferrioxamine, has anti-proliferative …

… Development of new methodologies such as combinatorial chemistry will be helpful in the
synthesis of inorganic compounds as therapeutic agents. Similarly, the action of metal comp…