… industry in the development of nonpeptide ligands such as the potent ORL1 agonist, Ro
64–… ligands with an emphasis on their potential therapeutic utility in various human disorders. …

Histamine was already known as a chemical compound before its presence in mammals
was established early this century. It has lasted until the 1920s before a physiological role for …

… in attempting to map the ligand-binding domains of the D2 and … D3-selective ligands, is also
presented in this review. … selective ligands is determining if newly developed ligands have …

… PPAR-γ ligands have also been shown to inhibit major … In the present review the crucial role
of PPAR-γ ligands in … , PPAR-γ ligands seem to represent potential therapeutic agents in the …

… Recent advances in inorganic chemistry have made possible formation of number of transition
metal complexes with organic ligand of interest, which can be used as therapeutic agent. …

… In the present review we have provided, without demanding completeness, a brief overlook
on the potential of G4 ligands as therapeutic agents in cancer (Table 1). In particular, we …

… Modified analogs of riboswitches natural ligands have thus been … thus serve as novel
therapeutic agents that have been studied in … ligands can lead to promising RNA-targeting agents. …

… a | The blue bars represent the total number of therapeutic agents targeting ligands (291
agents) that have entered clinical trials each year beginning in 1992, which is the first year in …

… Immunophilin ligands (IPLs) bind to immunophilins and are … -IPLs as potential therapeutic
agents for Parkinson's disease. … ligands: evaluation of their therapeutic potential for the …

… therapeutic agents, but in addition, modular organisation of structures of biological proteins,
and the identification of localised ligand-… ligand:receptor interaction sites is more advanced. …