… diagnosis, treatment, and management of patients with sepsis. … pathogenesis and the target
of clinical diagnosis of sepsis, with the goal of enhancing the current understanding of sepsis…

… knowledge of sepsis pathogenesis and potential novel approaches to the treatment of this …
PD1–PDL1 axis as a potential therapeutic target in sepsis 42 . Monocyte PDL1 expression is …

… Additionally, we highlight important targets involved in sepsis-related regulatory … in potential
therapeutic drugs that specifically target these signaling pathways and paramount targets, …

… In summary, while the innate immune system is rich in potential therapeutic targets and
remains a promising area of research, as has been demonstrated by the study of cytokines in this …

… evolution of sepsis therapy (Table 1) and identifies possible causes for why rational therapies
failed in human trials. In addition, this article examines potential future sepsis targets and …

… activation appears to be a potential therapeutic candidate for sepsis. Stem Cells in Sepsis
… understanding, and may shed light on novel therapeutic targets for the treatment of sepsis. …

… actions in recent years, a number of therapeutic strategies targeting cytokines and other …
septic patients. Their current role in the treatment of sepsis is discussed later in this review. …

… Thus, strategies focusing on further therapy targets are an important area of interest …
pathogenesis of sepsis, focusing on recent advances and on possible targets for adjunctive therapy. …

… into additional therapeutic agents directed against novel targets. Following a review of
recent advances in sepsis treatment, we briefly discuss a few of the new, promising therapeutic …

… that might contribute to the pathogenesis of lethal sepsis. To identify such mediators, we …
Thus, there is ongoing research for other clinically feasible therapeutic targets (such as IL-3) …