… Because embryo culture has been reported to affect DNA methylation 38 , we determined
5 mC profiles during preimplantation development following in vitro fertilization (IVF). We also …

… stages and no evidence of remethylation by the blastocyst stage. We suggest that the dramatic
differences in DNA methylation … role of DNA methylation in early mammalian embryonic …

… pre-implantation embryos, we hypothesized that allele-specific CHMs may exist widely in
pre-implantation embryos. To … CHMs in pre-implantation embryos, we established GG and AG …

… DNA methylation influences primate early embryogenesis. Our results refine the current
knowledge on DNA methylation … resource for future studies on primate embryonic development. …

… of DNA methylation during early embryo development and PGC … Preimplantation embryo
development represents a unique and exceptional example of dynamic DNA methylation…

… , we found drastic de novo DNA methylation during human preimplantation … preimplantation
embryos used in this study exhibited normal morphology with appropriate developmental …

… demethylation that occurs during preimplantation development [41]. The maintenance of
LINE1 elements in the methylated state in preimplantation embryos has been suggested to …

… human gametes and preimplantation embryos have shed light … knowledge regarding global
and imprinted DNA methylation … and human DNA methylation dynamics during gamete and …

… This mechanism, which allows efficient erasure of global DNA methylation, is relevant in
multiple biological processes. In preimplantation embryos, erasure of DNA methylation marks …

… is considered stable and heritable, and, accordingly, global changes to DNA methylation …
germ cells and preimplantation embryos. At these stages, methylation marks are erased and …