Inhibition of programmed death‐1 decreases neointimal hyperplasia after patch angioplasty

H Bai, Z Wang, M Li, P Sun, S Wei… - … Research Part B …, 2021 - Wiley Online Library
Programmed death-1 (PD-1) antibody treatment decreases tumor cell proliferation and …
neointimal hyperplasia. We hypothesized that inhibition of PD-1 inhibits neointimal hyperplasia in …

[HTML][HTML] Programmed death-1 mediates venous neointimal hyperplasia in humans and rats

P Sun, Z Wang, W Liu, M Li, S Wei, Y Xu, Z Qiao… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
… Venous neointimal hyperplasia can be a problem after vein interventions. We hypothesized
that inhibiting programmed death-1 (PD-1) can decrease venous neointimal hyperplasia in a …

Enhanced intimal proliferation upon injury to pre-existing neointima and resistance of neointimal cells to cell death

LM Myllärniemi, SK Rasilainen, KB Lemström… - Cardiovascular …, 1999 - Elsevier
… recently programmed cell death has been suggested to contribute to remodeling and neointimal
… suggested as a possible mechanism leading to intimal hyperplasia (5). Previous studies …

Analysis of arterial intimal hyperplasia: review and hypothesis

VM Subbotin - Theoretical Biology and Medical Modelling, 2007 - Springer
… Third, all members of our society have a natural desire to remain healthy until death at an …
Besides, we already know that even the most rigidly programmed morphogenic processes …

The intimal hyperplastic response

E Allaire, AW Clowes - The Annals of thoracic surgery, 1997 - Elsevier
… stabilizes intimal growth. Hence, the mere presence of endothelial cells can influence intimal
… proliferation, extracellular matrix accumulation, intimal hyperplasia, and vessel narrowing. …

Noncoding RNAs in vascular smooth muscle cell function and neointimal hyperplasia

EM Maguire, Q Xiao - The FEBS journal, 2020 - Wiley Online Library
… dered by VSMC senescence and apoptosis (ie programmed cell death) [9]. Importantly, NIH
… cardiac tissues, leading to the onset of cell death in the heart muscle wall, also known as …

Increased Apoptotic Cell Death in the Neointima after Stent‐Based Vascular Irradiation: Role of Radiation‐Induced Apoptosis for Restenosis Reduction

C HEHRLEIN, M KOLLUM, A ARAB… - Journal of …, 1999 - Wiley Online Library
neointimal volumes within bodies of 'lP radioactive coronary stents. Radiotherapy induces
programmed cell death (… incorporating radioisotopes reduce neointimal hyperplasia in vivo by …

Forkhead transcription factors inhibit vascular smooth muscle cell proliferation and neointimal hyperplasia

MR Abid, K Yano, S Guo, VI Patel, G Shrikhande… - Journal of Biological …, 2005 - ASBMB
neointimal hyperplasia. These data suggest that FoxO activity inhibits VSMC proliferation
and activation and that this signaling axis may represent a therapeutic target in vasculopathic …

Photodynamic therapy induces apoptosis in intimal hyperplastic arteries

GM LaMuraglia, J Schiereck, J Heckenkamp… - The American journal of …, 2000 - Elsevier
… is maintained without a delayed intimal hyperplastic response. Mechanisms regulating these
… induces cell death by apoptosis, a morphologically defined form of programmed cell death. …

P53 Gene Therapy Modulates Signal Transduction in the Apoptotic and Cell Cycle Pathways Downregulating Neointimal Hyperplasia

T Jacob, A Hingorani, E Ascher - … and endovascular surgery, 2012 - journals.sagepub.com
… In a previous experiment, we showed a significant reduction in intimal hyperplasia (IH) …
(programmed cell death) in vivo. We consistently obtained up to 96% reduction in neointimal