Pathological mechanisms in progressive multiple sclerosis

DH Mahad, BD Trapp, H Lassmann - The Lancet Neurology, 2015 - thelancet.com
progressive stages of the disease. We propose that the inflammatory demyelinating disease
process in early multiple sclerosis … that treatment of progressive multiple sclerosis should be …

Progressive multiple sclerosis: pathology and pathogenesis

H Lassmann, J Van Horssen, D Mahad - Nature Reviews Neurology, 2012 - nature.com
… inflammatory process and pathogenetic mechanisms in multiple sclerosis (MS). … progressive
MS and discusses new data on the mechanisms underlying its pathogenesis. In progressive

Treatment of progressive multiple sclerosis: what works, what does not, and what is needed

A Feinstein, J Freeman, AC Lo - The Lancet Neurology, 2015 - thelancet.com
… Therefore, the half of patients with multiple sclerosis who have progressive disease have …
of how we can help patients with primary progressive multiple sclerosis (PPMS) and SPMS. …

Primary-progressive multiple sclerosis

DH Miller, SM Leary - The Lancet Neurology, 2007 - thelancet.com
About 10–15% of patients with multiple sclerosis (MS) present with gradually increasing
neurological disability, a disorder known as primary-progressive multiple sclerosis (PPMS). …

Progressive multiple sclerosis: from pathogenic mechanisms to treatment

J Correale, MI Gaitán, MC Ysrraelit, MP Fiol - Brain, 2017 - academic.oup.com
… may be key processes in progressive disease. Interfering with these … clinical trials in
progressive multiple sclerosis have yielded … involved in progressive multiple sclerosis, correlations …

Progressive multiple sclerosis

M Bradl, H Lassmann - Seminars in immunopathology, 2009 - Springer
… Relapsing/remitting multiple sclerosis (RRMS) appears to be largely … progressive disease
(primary progressive multiple sclerosis, PPMS and secondary progressive multiple sclerosis, …

Defining secondary progressive multiple sclerosis

J Lorscheider, K Buzzard, V Jokubaitis, T Spelman… - Brain, 2016 - academic.oup.com
… of secondary progressive multiple sclerosis has been lacking… definition for secondary
progressive multiple sclerosis, to … definitions for secondary progressive multiple sclerosis and first …

Secondary progressive multiple sclerosis: new insights

BAC Cree, DL Arnold, J Chataway, T Chitnis, RJ Fox… - Neurology, 2021 - AAN Enterprises
In most cases, multiple sclerosis (MS) begins with a relapsing… relapses and is termed secondary
progressive MS (SMPS). … remitting to a secondary progressive disease course not only …

Progressive multiple sclerosis: from pathophysiology to therapeutic strategies

S Faissner, JR Plemel, R Gold, VW Yong - Nature reviews drug …, 2019 - nature.com
… Drug Administration as therapy for secondary progressive multiple sclerosis (SPMS), and …
(which is approved for primary progressive multiple sclerosis (PPMS)) and rituximab. Other …

Primary progressive multiple sclerosis.

AJ Thompson, CH Polman, DH Miller… - Brain: a journal of …, 1997 - academic.oup.com
… patients with secondary progressive multiple sclerosis of similar physical disability. They
suggest that this relates to progressive multiple sclerosis, but not in the primary progressive type …