… during neoplastic transformation of prostate cells, which suggests that … of prostate cancer
outcome. Although treatment for localized prostate cancer can be curative, the development of …

… Several studies have reported that calcium may play an important role in prostate cancer
development. The strongest evidence for an association between calcium and risk of …

… , development and progression of prostate cancer. It may become possible to distinguish
between indolent and aggressive types reserving radical treatment for the latter ones. Although …

… of prostate cancer progression 38 has led to the development of several new therapeutic
approaches. One example is abiraterone acetate, an inhibitor of 17α-hydroxylase and C17,20 …

… Genetically engineered mouse models have been generated to study the molecular basis
of prostate cancer (PCa) development, progression, and metastasis. Selection of a prostate-…

… test for clinically significant prostate cancer continue to drive efforts to develop better tests. …
of multiple proteins hold great promise, 48 but remain at early stages of development. …

… cancer in men worldwide [1] and the leading site for cancer … one in six men will develop
prostate cancer in their lifetime [2]. … contributors to prostate cancer development and progression …

… each patient with prostate cancer, one tumor before and one tumor after the development of
… identify gene abnormalities in tumors after the development of hormone escape that are not …

… prostate cancer (P < ,001). Men with a father or brother affected were twice as likely to develop
prostate cancer … the development of prostate cancer. Men with a positive family history of …

… prostate cancer progression. Nevertheless, several candidate genes and pathways have been
implicated in prostate cancer development… role in prostate cancer pathogenesis has been …