Anticancer activity of a novel selective CYP17A1 inhibitor in preclinical models of castrate-resistant prostate cancer
PJ Toren, S Kim, S Pham, A Mangalji, H Adomat… - Molecular cancer …, 2015 - AACR
… the anticancer activity of VT-464 compared with abiraterone (ABI) in castrate-resistant prostate
cancer cell lines and xenograft models … The MR49F xenograft model was used to compare …
cancer cell lines and xenograft models … The MR49F xenograft model was used to compare …
Flavopiridol (L86-8275): selective antitumor activity in vitro and activity in vivo for prostate carcinoma cells.
M Drees, WA Dengler, T Roth, H Labonte, J Mayo… - … Association for Cancer …, 1997 - AACR
… tumor and five cell line-derived xenografts established by serial passage in nude mice in our
laboratory were used as tumor models for in … -stage sc growing prostate cancer xenografts. …
laboratory were used as tumor models for in … -stage sc growing prostate cancer xenografts. …
Antitumor activity of the histone deacetylase inhibitor MS‐275 in prostate cancer models
… -sensitive and hormone refractory prostate cancer cell lines. Then, we tested the antitumor
activity of MS-275 in several prostate cancer models including subcutaneous and intratibia …
activity of MS-275 in several prostate cancer models including subcutaneous and intratibia …
Protective immunosurveillance and therapeutic antitumor activity of γδ T cells demonstrated in a mouse model of prostate cancer
Z Liu, IEA Eltoum, B Guo, BH Beck… - The Journal of …, 2008 - journals.aai.org
… findings derived using the TRAMP model of mouse prostate cancer are presented in this …
for treating human prostate cancer, or other common human cancers of epithelial origin, …
for treating human prostate cancer, or other common human cancers of epithelial origin, …
Enigmol: A Novel Sphingolipid Analogue with Anticancer Activity against Cancer Cell Lines and In vivo Models for Intestinal and Prostate Cancer
H Symolon, A Bushnev, Q Peng, H Ramaraju… - Molecular cancer …, 2011 - AACR
… with suppression of colon cancer (20, 21), and then its efficacy was evaluated using mouse
models for colon and prostate cancer. Enigmol displayed anticancer activity in all these …
models for colon and prostate cancer. Enigmol displayed anticancer activity in all these …
[HTML][HTML] Antitumor activity of alkylphospholipid edelfosine in prostate cancer models and endoplasmic reticulum targeting
ELH Dakir, C Gajate, F Mollinedo - Biomedicine & Pharmacotherapy, 2023 - Elsevier
… Here, we present evidence, by using different in vitro and in vivo prostate cancer models,
that edelfosine exerts a significant antitumor activity against prostate cancer, promoting …
that edelfosine exerts a significant antitumor activity against prostate cancer, promoting …
… CYP17 inhibitors/antiandrogens: synthesis, in vitro biological activity, pharmacokinetics, and antitumor activity in the LAPC4 human prostate cancer xenograft model
VD Handratta, TS Vasaitis, VCO Njar… - Journal of medicinal …, 2005 - ACS Publications
… antitumor activity against a prostate cancer tumor to an extent that is superbly more effective
than castration. These impressive biological activities … treatment of prostate cancer in humans…
than castration. These impressive biological activities … treatment of prostate cancer in humans…
Synthesis, molecular modeling, in vivo study and anticancer activity against prostate cancer of (+)(S)-naproxen derivatives
… at the in vitro anticancer activity studies of the triazole-… prostate cancer cell line led to the in
vivo studies. In male nude mice in which prostate cancer was established with LNCaP cancer …
vivo studies. In male nude mice in which prostate cancer was established with LNCaP cancer …
Antitumor activity of NLG207 (formerly CRLX101) in combination with enzalutamide in preclinical prostate cancer models
KT Schmidt, CH Chau, JD Strope, ADR Huitema… - Molecular cancer …, 2021 - AACR
… had significant antitumor activity in two different preclinical prostate cancer models harboring
clinically … Antitumor activity of NLG207 and enzalutamide was demonstrated in both …
clinically … Antitumor activity of NLG207 and enzalutamide was demonstrated in both …
Antitumor activity of mifepristone in the human LNCaP, LNCaP‐C4, and LNCaP‐C4‐2 prostate cancer models in nude mice
MF El Etreby, Y Liang, MH Johnson, RW Lewis - The Prostate, 2000 - Wiley Online Library
… If the observed antitumor activity of mifepristone in our prostate cancer models is PR-mediated,
the prostate cancer tissue in our models should contain an adequate PR concentration. …
the prostate cancer tissue in our models should contain an adequate PR concentration. …
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