… in prostate cancer, we tested, in vitro and in vivo models, the differential biological effects
of this agent in a wide panel of androgen-sensitive and androgen-independent tumor cells. …

… To better understand this process, we have studied the effects of different statins in our in-house,
well-categorised models of CaP behaviour, evaluating the differential effects of specific …

… tumor progression. Consequently, we have evaluated the relative effect of prostate cancer
… differentiation in established cellular models of prostate cancer. These studies reveal that …

… multiple pathways that impact prostate cancer cell growth, and that the effects of … model.
Our results suggest that resveratrol exerts differential effects in these in vitro and in vivo models…

… endothelial cell death in this model. Rather, growth … tumor cell death. Together, our results
confirm that bortezomib is active in preclinical models of human prostate cancer, but its effects …

… of their impact on cell behavior has not been conducted. The prostate cancer cell line … node
metastasis, is a commonly used model system in prostate cancer research. However, the cells…

… To evaluate the differential effects of PZsc and TZsc on PCa development as judged by
growth factor expression patterns, we measured the mRNA expression levels of basic fibroblast …

… effect of changes in IGF-IR expression during tumor progression on AR signaling. We demonstrate
that, in the M12 human prostate cancer … from an intraprostatic tumor or a metastasis. In …

… However, from a Three Rs perspective, alternative models should be considered to replace
… models for use within the context of prostate cancer research, including mathematical models…

… of low-grade prostate cancer in men. Our data on a differential effect of androstenedione
also suggest that some high-grade prostate cancers may not require androgen for progression. …