… throughout the currently accepted cancer hallmarks, with emphasis on … , adding another
dimension of complexity to cancer … the glycosylation-mediated promotion of cancer hallmarks, …

… hallmarks. Here we argue that the process of glycosylation is an enabling characteristic that
is causally associated with the acquisition of all the proposed cancer hallmark capabilities (…

… of glycosylation with all the hallmarks of cancer. The … glycosylation is linked to tumor
initiation, progression and metastasis. Hence, it can be considered as a new hallmark of cancer …

… (GTs) (O-glycosylation) [25]. Changes in protein glycosylation can alter protein
conformation, oligomerization, and turnover, thus resulting in altered cell signaling pathways. …

… Alteration of glycosylation, a hallmark of cancer, results in the production of … in cancer would
likely facilitate diagnosis and treatment. In this chapter, the alteration of protein glycosylation …

… This review discusses the role of galectins as “on-and-off” switchers of different hallmarks
of cancer, illustrating relevant examples of their contribution to tumor progression (Fig. 1). …

… various hallmark characteristics of cancer. This review supports the concept of glycosylation
as a major hallmark of cancer and is an enabling characteristic for other hallmarks of cancer. …

… ways to the hallmarks of cancer and assist … protein glycosylation, namely increased β1,6-GlcNAc-branched
N-glycans and decreased O-mannosylation glycans that contributes to cancer …

… Acquisition of the cancer hallmarks is made possible in part by the development of
genomic instability in cancer cells which generates random mutations and chromosomal …

… lead to the progression of cancer. While a majority of studies have investigated protein
glycosylation changes in cancer cell lines and tumour tissue for individual cancers, the review …