The role of particulate pollutants in pulmonary inflammation and asthma: evidence for the involvement of organic chemicals and oxidative stress

AE Nel, D Diaz-Sanchez, N Li - Current opinion in pulmonary …, 2001 - journals.lww.com
… regarding the mode of action of particulate pollutants, we have provided preliminary …
stress by organic particulate compounds may contribute to pulmonary inflammation and toxicity. …

Inflammatory effects of particulate matter air pollution

RD Arias-Pérez, NA Taborda, DM Gómez… - … Science and Pollution …, 2020 - Springer
pollution is an important cause of non-communicable diseases globally with particulate
matter (PM) as one of the main air pollutants… , and chronic obstructive pulmonary disease (COPD)…

Exposure to fine particulate air pollution is associated with endothelial injury and systemic inflammation

CA Pope III, A Bhatnagar, JP McCracken… - Circulation …, 2016 - Am Heart Assoc
… was positively associated with markers of endothelial injury and systemic inflammation. The
evidence suggests that inhalation and pulmonary deposition of PM 2.5 triggers inflammatory

Particulate matter exposure induces persistent lung inflammation and endothelial dysfunction

E Tamagawa, N Bai, K Morimoto… - … of Physiology-Lung …, 2008 - journals.physiology.org
… lung inflammation induced by exposure to ambient particulate matter air pollution relates to
… Interestingly, they also reported that pulmonary inflammation reached a maximum at 24 h, …

Oxidative stress and inflammation generated DNA damage by exposure to air pollution particles

P Møller, PH Danielsen, DG Karottki, K Jantzen… - … research/Reviews in …, 2014 - Elsevier
inflammation. We investigated this hypothesis by comparing ROS production, inflammation
and oxidatively damaged DNA in different experimental systems investigating air pollution

Systemic microvascular dysfunction and inflammation after pulmonary particulate matter exposure

TR Nurkiewicz, DW Porter, M Barger… - Environmental …, 2006 - ehp.niehs.nih.gov
… We have previously shown that acute pulmonary exposure to PM impairs or abolishes … of
pulmonary PM exposure on systemic microvascular function and to identify local inflammatory

Inflammatory markers and particulate air pollution: characterizing the pathway to disease

A Zeka, JR Sullivan, PS Vokonas… - International journal …, 2006 - academic.oup.com
… of mediators—pro-inflammatory cytokines due to injury of the pulmonary alveoli 33,35,36
or … particulate pollution on the inflammatory markers. Obesity represents a pro-inflammatory

Neurogenic inflammation and particulate matter (PM) air pollutants

B Veronesi, M Oortgiesen - Neurotoxicology, 2001 - Elsevier
… the inflammatory responsiveness to PM. In summary, this review proposes a mechanism by
which neurogenic elements initiate and sustain PM-mediated airway inflammationpulmonary

Reactive oxygen species in pulmonary inflammation by ambient particulates

F Tao, B Gonzalez-Flecha, L Kobzik - Free Radical Biology and Medicine, 2003 - Elsevier
… Exacerbation of pulmonary inflammation in susceptible people (eg, asthmatics, COPD
patients) appears to be a central mechanism by which PM exert their toxicity. Health effects are …

Chronic residential exposure to particulate matter air pollution and systemic inflammatory markers

B Hoffmann, S Moebus, N Dragano… - Environmental …, 2009 - ehp.niehs.nih.gov
… Plausible mechanisms for the effect of air pollution on atherogenesis include the induction
of low-grade pulmonary inflammation with a secondary systemic inflammatory response. …