Quantitative analysis in the characterization and optimization of protein crystal growth

CW Carter, Y Yin - … Section D: Biological Crystallography, 1994 - journals.iucr.org
crystals. Designed factorial experiments and quantitative analysis of variations in crystal
growth … The elements of experimental design and analysis described here are summarized in …

New strategies for protein crystal growth

JM Wiencek - Annual review of biomedical engineering, 1999 - annualreviews.org
… provide a clearer picture ofprotein crystal nucleation and growth. This ever … methods to
produce protein crystals as well as means toimprove the diffraction quality of such protein crystals

Quantitative analysis of crystal growth: Tryptophanyl-tRNA synthetase crystal polymorphism and its relationship to catalysis

CW Carter Jr, S Doublié, DE Coleman - Journal of molecular biology, 1994 - Elsevier
… We show tha-t quantitative analysis of replicated, full-factorial crystal growth experiments
and, by implication, similar studies of a wide variety of other phenomena, can be a powerful tool …

Quantitative analysis of molecular-level DNA crystal growth on a 2D surface

J Lee, S Hamada, SU Hwang, R Amin, J Son… - Scientific Reports, 2013 - nature.com
… systematic and quantitative study of the nucleation and growth mechanism of DNA crystals by
… Once these growth behaviors are well established, they will serve as an important guide in …

Statistical design of experiments for protein crystal growth and the use of a precrystallization assay

CW Carter Jr, ET Baldwin, L Frick - Journal of Crystal Growth, 1988 - Elsevier
… of protein crystal growers, evidencedby therapidly ing between 20 and 35 experiments to
screen conditions for growing crystals of … we use more serious qualitative defect is its inability to …

Elementary processes of protein crystal growth

PG Vekilov - Progress in crystal growth and characterization of …, 1993 - Elsevier
… its great advantages in crystal growth from solution studies of … quantitative assessment of
various surface features on the … that crystallization trials to find optimal protein crystal growth

Importance of determination of crystal quality in protein crystals when performing high-resolution structural analysis

H Koizumi, R Suzuki, M Tachibana… - Crystal Growth & …, 2016 - ACS Publications
analysis. Therefore, it is important to determine whether the crystal quality of a protein crystal
under analysis … structures of protein molecules for X-ray structural analyses. We show that X-…

Promotion of protein crystal growth by actively switching crystal growth mode via femtosecond laser ablation

Y Tominaga, M Maruyama, M Yoshimura, H Koizumi… - Nature …, 2016 - nature.com
… the local crystal structure via femtosecond laser ablation. We demonstrate that protein
crystals with … To quantitatively evaluate such anisotropic crystal growth via laser ablation, the …

Resolving crystal polymorphisms by finding “stationary points” from quantitative analysis of crystal growth response surfaces

LF Kuyper, CW Carter Jr - Journal of crystal growth, 1996 - Elsevier
… The study of crystalline polymorphisms is a potentially … the quantitative analysis necessary
to realize this goal [18]. In this work, we have used the same quantitative methods to study a …

Microscopic model of protein crystal growth

AM Kierzek, P Pokarowski, P Zielenkiewicz - Biophysical Chemistry, 2000 - Elsevier
… Therefore, the simulations presented in this work show that protein crystal growth is difficult,
not only because it is difficult to find the proper crystallisation conditions, as even under ideal …