Quantitative assessment of DNA methylation: potential applications for disease diagnosis, classification, and prognosis in clinical settings

RM Brena, THM Huang, C Plass - Journal of molecular medicine, 2006 - Springer
… In this review, we address the significance of DNA methylation changes that result or lead …
quantitative techniques currently available for the detection and analysis of DNA methylation

Genome-wide quantitative assessment of variation in DNA methylation patterns

H Xie, M Wang, A De Andrade, MF Bonaldo… - Nucleic acids …, 2011 - academic.oup.com
… entropy to assess the variation in DNA methylation patterns … in DNA methylation patterns, (ii)
for a given locus, methylation … associated with variation in DNA methylation patterns and (iv) …

[HTML][HTML] Quantitative methodology is critical for assessing DNA methylation and impacts on correlation with patient outcome

AM Lim, ILM Candiloro, N Wong, M Collins, H Do… - Clinical …, 2014 - Springer
… were assessed by an orthogonal quantitative methodology. … significant methylation events
with the use of non-quantitative … of quantitative methodology to detect significant methylation

[HTML][HTML] Quantification of epigenetic biomarkers: an evaluation of established and emerging methods for DNA methylation analysis

N Redshaw, JF Huggett, MS Taylor, CA Foy… - BMC genomics, 2014 - Springer
DNA methylation is an important epigenetic mechanism in several human diseases, most
notably cancer. The quantitative analysis of DNA methylation patterns has the potential to …

Novel assay for quantitative analysis of DNA methylation at single-base resolution

H Yu, L Bai, G Tang, X Wang, M Huang, G Cao… - Clinical …, 2019 - academic.oup.com
… -treated DNA with the single-nucleotide polymorphism being the CpG after bisulfite
treatment. We developed an assay for the quantitative analysis of single-base methylation (QASM). …

Quantitative assessment of DNA methylation for the detection of cervical neoplasia in liquid-based cytology specimens

JH Kim, YD Choi, JS Lee, JH Lee, JH Nam, C Choi… - Virchows Archiv, 2010 - Springer
Previously, we have shown that methylation-specific PCR (MSP) analysis of a key panel of
genes may be useful as an ancillary tool for diagnosing squamous cell carcinomas (SCC) …

Quantitative analysis of DNA methylation profiles in lung cancer identifies aberrant DNA methylation of specific genes and its association with gender and cancer risk …

T Vaissière, RJ Hung, D Zaridze, A Moukeria, C Cuenin… - Cancer research, 2009 - AACR
… Here, we have applied quantitative profiling of DNA methylation states … methylation levels
of GSTP1 and CDH1 was observed, consistent with the notion that aberrant DNA methylation

A systematic comparison of quantitative high-resolution DNA methylation analysis and methylation-specific PCR

R Claus, S Wilop, T Hielscher, M Sonnet, E Dahl… - Epigenetics, 2012 - Taylor & Francis
quantitative assessment but not of MSP-derived methylation … relevance of quantitative DNA
methylation assessment. Taken … applied technique for DNA methylation assessment, our data …

Quantitative high-throughput analysis of DNA methylation patterns by base-specific cleavage and mass spectrometry

M Ehrich, MR Nelson, P Stanssens… - Proceedings of the …, 2005 - National Acad Sciences
… of all relevant aspects of DNA methylation, with most CpGs … conditions to quantitatively
assess methylation differences … demonstrate that the quantitative methylation results allow …

A systematic review and quantitative assessment of methylation biomarkers in fecal DNA and colorectal cancer and its precursor, colorectal adenoma

R Liu, X Su, Y Long, D Zhou, X Zhang, Z Ye… - … Research/Reviews in …, 2019 - Elsevier
… A number of studies have documented altered methylation levels in DNA extracted from …
review and quantitative assessment of existing studies to compare levels of DNA methylation in …