Quality by design approach for development and characterisation of solid lipid nanoparticles of quetiapine fumarate

S Agarwal, RSR Murthy… - … Computer-Aided Drug …, 2020 - ingentaconnect.com
Background: Quetiapine fumarate, a 2nd generation anti-… at developing, and characterising
potentially lymphatic absorbable Solid Lipid Nanoparticles (SLN) of quetiapine fumarate by …

Formulation and pharmaceutical development of quetiapine fumarate sustained release matrix tablets using a QbD approach

A Gavan, A Porfire, C Marina, I TOMUŢĂ - Acta Pharmaceutica, 2017 - hrcak.srce.hr
… in vitro release values is realized with the help of mathematical polynomial equations that
convert the dissolution profiles into parameters relating to the pharmaceutical characteristics of …

Identification and characterization of potential impurities of quetiapine fumarate

EU Stolarczyk, Ł Kaczmarek, K Eksanow… - … development and …, 2009 - Taylor & Francis
… The potential impurities of quetiapine fumarate were … to develop a new LC/MS/MS method
for separation and quantitative determination of related substances in quetiapine fumarate. …

In-vitro and pharmacodynamic characterization of solidified self microemulsified system of quetiapine fumarate

HC Vadlamudi, PR Yalavarthi, T Nagaswaram… - Journal of …, 2019 - Springer
Quetiapine fumarate has possessed low solubility and … Solubility of quetiapine was assessed
in various liquid vehicles (oils, … focused on the development of quetiapine loaded SMEDDS. …

Quality-by-Design Approach Development, Characterization, and In Vitro Release Mechanism Elucidation of Nanostructured Lipid Carriers for Quetiapine Fumarate …

O Ben Hadj Ayed, MA Lassoued, S Sfar - Journal of Pharmaceutical …, 2022 - Springer
… The objective of this work was to develop a new nanostructured lipid carrier (NLC) formulation
for the oral delivery of quetiapine fumarate (QTF) and assess the drug’s in vitro release …

[HTML][HTML] QbD-based design and characterization of mucoadhesive microspheres of quetiapine fumarate with improved oral bioavailability and brain biodistribution …

S Komati, S Swain, MEB Rao, BR Jena… - Bulletin of Faculty of …, 2018 - Elsevier
development and characterization of the sustained release mucoadhesive microspheres of
quetiapine fumarate… biopharmaceutical attributes of quetiapine fumarate from mucoadhesive …

Pharmacokinetic profile of the extended-release formulation of quetiapine fumarate (quetiapine XR): clinical implications

K Bui, W Earley, S Nyberg - Current medical research and opinion, 2013 - Taylor & Francis
… A series of studies were conducted to guide the development and characterise the
pharmacokinetics of extended-release quetiapine fumarate (quetiapine XR), a once-daily formulation …

Quetiapine Fumarate: A Review of Analytical Methods

A Hamsa… - Journal of …, 2023 - academic.oup.com
Quetiapine fumarate is an atypical antipsychotic drug used to treat schizophrenia, mania …
Quetiapine was developed in 1985 and approved for medical use in the USA in 1997. …

Preparation, characterization and evaluation of quetiapine fumarate solid lipid nanoparticles to improve the oral bioavailability

A Narala, K Veerabrahma - Journal of pharmaceutics, 2013 - Wiley Online Library
… of quetiapine fumarate by incorporating in solid lipid nanoparticles (SLN). Six quetiapine
fumarate SLN formulations were developed … Stable quetiapine fumarate SLNs having a mean …

[PDF][PDF] Formulation and evaluation of matrix-based sustained release tablets of quetiapine fumarate and the influence of excipients on drug release

P Gawali, A Gupta, S Kachare, S Kshirsagar - J Chem Pharm Res, 2012 - academia.edu
… to develop and characterize an oral sustain release drug delivery system for commonly
prescribed antipsychotic Quetiapine fumarate. … K100 LV and K4M CR was developed using wet …