Randomized phase III placebo-controlled trial of carboplatin and paclitaxel with or without the vascular disrupting agent vadimezan (ASA404) in advanced non–small …
PN Lara Jr, JY Douillard, K Nakagawa… - Journal of Clinical …, 2011 - ascopubs.org
… between the encouraging results of the randomized phase II trial of carboplatin/… randomized
phase III trial? The most likely explanation is that the smaller sample size of the phase II trial …
phase III trial? The most likely explanation is that the smaller sample size of the phase II trial …
Pemetrexed combined with Oxaliplatin or carboplatin as first-line treatment in advanced non–small cell lung cancer: a multicenter, randomized, phase II trial
GV Scagliotti, C Kortsik, GG Dark, A Price… - Clinical cancer …, 2005 - AACR
… In the present trial, we used a randomized phase II design in chemonaive patients with
locally advanced or metastatic NSCLC to simultaneously evaluate the activity of two regimens …
locally advanced or metastatic NSCLC to simultaneously evaluate the activity of two regimens …
A multicenter randomized phase II study of oral vs. intravenous vinorelbine in advanced non-small-cell lung cancer patients
J Jassem, R Ramlau, H Karnicka-Młodkowska… - Annals of oncology, 2001 - Elsevier
… Lung cancer is the leading cause of cancer death in industrialized countries. Non-small-cell
lung cancers (NSCLC) represent more than 80% of all lung cancers. The great majority of …
lung cancers (NSCLC) represent more than 80% of all lung cancers. The great majority of …
[HTML][HTML] … patient-reported outcomes of atezolizumab, carboplatin, and etoposide in extensive-stage small-cell lung cancer (IMpower133): a randomized phase I/III trial
AS Mansfield, A Każarnowicz, N Karaseva, A Sánchez… - Annals of oncology, 2020 - Elsevier
… on day 1 of each cycle (induction phase), followed by iv atezolizumab or placebo according
to randomized assignment (maintenance phase), until unacceptable toxicity or disease …
to randomized assignment (maintenance phase), until unacceptable toxicity or disease …
[HTML][HTML] A randomized phase II study of ganetespib, a heat shock protein 90 inhibitor, in combination with docetaxel in second-line therapy of advanced non-small cell …
S Ramalingam, G Goss, R Rosell, G Schmid-Bindert… - Annals of oncology, 2015 - Elsevier
Background This trial was designed to evaluate the activity and safety of ganetespib in
combination with docetaxel in advanced non-small cell lung cancer (NSCLC) and to identify …
combination with docetaxel in advanced non-small cell lung cancer (NSCLC) and to identify …
[HTML][HTML] … results from a randomized phase III trial comparing gefitinib with carboplatin–paclitaxel for chemo-naïve non-small cell lung cancer with sensitive EGFR gene …
A Inoue, K Kobayashi, M Maemondo, S Sugawara… - Annals of oncology, 2013 - Elsevier
Background NEJ002 study, comparing gefitinib with carboplatin (CBDCA) and paclitaxel (PTX;
Taxol) as the first-line treatment for advanced non-small cell lung cancer (NSCLC) …
Taxol) as the first-line treatment for advanced non-small cell lung cancer (NSCLC) …
Randomized phase II study of gefitinib versus erlotinib in patients with advanced non-small cell lung cancer who failed previous chemotherapy
… In this randomized, single-center, non-comparative phase II trial, the efficacy and safety of …
-line therapy for advanced non-small cell lung cancer (NSCLC). PATIENTS AND METHODS: …
-line therapy for advanced non-small cell lung cancer (NSCLC). PATIENTS AND METHODS: …
AENEAS: A randomized phase III trial of aumolertinib versus gefitinib as first-line therapy for locally advanced or metastaticnon–small-cell lung cancer with EGFR exon …
S Lu, X Dong, H Jian, J Chen, G Chen… - Journal of Clinical …, 2022 - ascopubs.org
… AENEAS was a multicenter, double-blind, randomized phase III trial conducted at 53
study sites in mainland China (Data Supplement, online only). The trial was conducted in …
study sites in mainland China (Data Supplement, online only). The trial was conducted in …
… of early versus late hyperfractionated thoracic irradiation concurrently with chemotherapy in limited disease small-cell lung cancer: a randomized phase II study of the …
DV Skarlos, E Samantas, E Briassoulis, E Panoussaki… - Annals of oncology, 2001 - Elsevier
… (HTRT) in limited disease (LD) small cell lung cancer (SCLC) is associated with a high response
… Group (HeCOG) performed a multicenter randomized phase II study in patients with LD …
… Group (HeCOG) performed a multicenter randomized phase II study in patients with LD …
[HTML][HTML] … results for OAK: a randomized phase III study of atezolizumab versus docetaxel in patients with previously treated advanced non–small cell lung cancer
L Fehrenbacher, J von Pawel, K Park… - Journal of thoracic …, 2018 - Elsevier
… OAK (NCT02008227) is a randomized phase III study comparing the efficacy and safety of
… However, after the randomized phase II POPLAR study demonstrated survival benefit with …
… However, after the randomized phase II POPLAR study demonstrated survival benefit with …