… We previously developed platforms for rapid synthesis of … platform of rapid synthesis of
molecular glues (Rapid-Glue) via … two highly selective GSPT1 molecular glues through direct …

… We highlight three in vitro label-free IDMs that successfully discovered molecular glues in
this … from our analysis is the success of molecular docking, which has been proven to rapidly …

… The concept of protein degradation is concerned with molecular glues, which form part of
the broader field of Targeted Protein Degradation (TPD). Next, pharmacochemical strategies …

… discovery and design strategies are emerging rapidly. In this review, we aim to highlight the
recent advances in molecular glues for … molecular glues into therapeutic agents. In particular, …

… ligand library for molecular glue degraders with backend chemoproteomic and quantitative
proteomic approaches would provide rapid discovery of molecular glue degraders and their …

… This study demonstrated the utility of coupling covalent ligand screening with chemical
and quantitative proteomics platforms for the rapid discovery of molecular glues. …

… in drug discovery practices for molecular glue degraders. We … progression of molecular
glues in drug discovery pipelines … interest in molecular glue compounds is rapidly expanding …

… allow for the transfer of the first ubiquitin molecule from the E2 enzyme to an accessible lysine
residue on the POI. This is followed by rapid transfer of additional ubiquitin units leading to …

… The development of chemical stabilizers of the CDC34A-ubiquitin complex illustrates a
general strategy for de novo discovery of molecular glue compounds that stabilize weak protein …

… However, the identification of molecular glues from scratch and … Here we review the
recently discovered molecular glues, … molecular glues, and the implications for drug discovery …