Heterogeneous Distribution of EGFR Mutations Is Extremely Rare in Lung Adenocarcinoma
… lung adenocarcinoma with lymph node metastasis and EGFR mutation to compare the
mutation … female patients with lung adenocarcinoma who had wild-type EGFR and lymph node …
mutation … female patients with lung adenocarcinoma who had wild-type EGFR and lymph node …
[HTML][HTML] Distinct epidemiology and clinical consequence of classic versus rare EGFR mutations in lung adenocarcinoma
Z Lohinai, MA Hoda, K Fabian, G Ostoros… - Journal of thoracic …, 2015 - Elsevier
… On the basis of the COSMIC database (retrieved at July 28, 2014), we found synonymous
and rare EGFR gene mutations already published in lung cancer (N = 33 mutations) or in …
and rare EGFR gene mutations already published in lung cancer (N = 33 mutations) or in …
[HTML][HTML] Rare epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer
… rare EGFR mutations in patients, our understanding of the biology of … rare EGFR mutations
is poor compared to classical mutations. In particular, clinical data focused on these mutations …
is poor compared to classical mutations. In particular, clinical data focused on these mutations …
… of common and rare EGFR mutations in response to EGFR tyrosine kinase inhibitors and platinum-based chemotherapy in patients with non-small cell lung cancer
… Our findings suggested that only patients with rare EGFR mutations could receive platinum-…
and short PFS in response to EGFR-TKIs. Consequently, EGFR-TKIs could be reserved as a …
and short PFS in response to EGFR-TKIs. Consequently, EGFR-TKIs could be reserved as a …
[HTML][HTML] Uncommon EGFR mutations in lung adenocarcinoma: features and response to tyrosine kinase inhibitors
A Brindel, W Althakfi, M Barritault, E Watkin… - Journal of Thoracic …, 2020 - ncbi.nlm.nih.gov
… In conclusion, uncommon EGFR mutations may be associated with a poor outcome and the
… in cases of double uncommon mutations and such patients should be treated accordingly. …
… in cases of double uncommon mutations and such patients should be treated accordingly. …
A comprehensive review of uncommon EGFR mutations in patients with non-small cell lung cancer
HY Tu, EE Ke, JJ Yang, YL Sun, HH Yan, MY Zheng… - Lung Cancer, 2017 - Elsevier
… reviewed the prevalence of uncommon EGFR mutations and their sensitivity to EGFR-TKIs. …
of uncommon EGFR mutation in Chinese lung cancer patients and their sensitivity to EGFR-…
of uncommon EGFR mutation in Chinese lung cancer patients and their sensitivity to EGFR-…
Uncommon EGFR mutations in advanced non-small cell lung cancer
… incidence of uncommon EGFR mutations and summarizes reported outcomes when treated
with EGFR-TKIs. … Exon 20 insertions in EGFR are the most prevalent of the uncommon EGFR …
with EGFR-TKIs. … Exon 20 insertions in EGFR are the most prevalent of the uncommon EGFR …
Clinicopathological characteristics of lung adenocarcinoma with compound EGFR mutations
… of lung adenocarcinoma with compound EGFR mutations … of lung adenocarcinomas
with compound EGFR mutations. We … EGFR mutations with common or uncommon single-mutation …
with compound EGFR mutations. We … EGFR mutations with common or uncommon single-mutation …
Characterization of common and rare mutations in EGFR and associated clinicopathological features in a large population of Chinese patients with lung cancer
B Wei, P Ren, C Zhang, Z Wang, B Dong… - … -Research and Practice, 2017 - Elsevier
… of EGFR mutations. To address the issue, we studied a cohort of 456 Chinese lung cancer
… rare EGFR mutations, and investigated corresponding clinicalpathological associations. …
… rare EGFR mutations, and investigated corresponding clinicalpathological associations. …
[HTML][HTML] Treatment of uncommon EGFR mutations in non-small cell lung cancer: new evidence and treatment
T Zhang, B Wan, Y Zhao, C Li, H Liu, T Lv… - … lung cancer research, 2019 - ncbi.nlm.nih.gov
… In China, it is also the most common cancer and leading cause of cancer-related … (EGFR)
mutations. NSCLC harboring EGFR mutations constitutes about 10–20% of all lung cancer …
mutations. NSCLC harboring EGFR mutations constitutes about 10–20% of all lung cancer …
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