[HTML][HTML] CPT1A promotes anoikis resistance in esophageal squamous cell carcinoma via redox homeostasis

T Tian, Y Lu, J Lin, M Chen, H Qiu, W Zhu, H Sun… - Redox biology, 2022 - Elsevier
anoikis resistance in vitro and in vivo by disrupting the NADPH supply to imbalance the redox
homeostasis. In … of CPT1A mediated FAO in anoikis resistance and indicated that CPT1A …

ZNF32 induces anoikis resistance through maintaining redox homeostasis and activating Src/FAK signaling in hepatocellular carcinoma

K Li, G Zhao, J Ao, D Gong, J Zhang, Y Chen, J Li… - Cancer letters, 2019 - Elsevier
… Taken together, our study indicated that ZNF32 induced the anoikis resistance of HCC cells
by maintaining redox homeostasis and activating Src/FAK signaling, implicating ZNF32 as a …

[HTML][HTML] HBXIP induces anoikis resistance by forming a reciprocal feedback loop with Nrf2 to maintain redox homeostasis and stabilize Prdx1 in breast cancer

X Zhou, L Li, X Guo, C Zhang, Y Du, T Li, K Tong… - NPJ Breast …, 2022 - nature.com
Anoikis resistance is an essential prerequisite for tumor metastasis, but the underlying …
loop contributes to anoikis resistance by maintaining redox homeostasis and inhibiting JNK1 …

[HTML][HTML] ENO2 promotes anoikis resistance in anaplastic thyroid cancer by maintaining redox homeostasis

Y Zhang, X Ji, Y Wang - Gland Surgery, 2024 - ncbi.nlm.nih.gov
… cell invasion, anoikis resistance, and the … homeostasis and anoikis resistance in ATC cells.
By manipulating ENO2 expression, we observed a profound reversal of anoikis resistance

[HTML][HTML] Mechanisms for modulating anoikis resistance in cancer and the relevance of metabolic reprogramming

FO Adeshakin, AO Adeshakin, LO Afolabi, D Yan… - Frontiers in …, 2021 - frontiersin.org
… glucose present in the cell was used to fuel PPP for redox homeostasis. The enhanced PPP
activity subsequently fostered anoikis resistance in these cells (90). The treatment of MDA-…

[HTML][HTML] Role of phytochemicals in perturbation of redox homeostasis in cancer

S Gaikwad, SK Srivastava - Antioxidants, 2021 - mdpi.com
… regulator of anoikis [59,60]. Additionally, ROS has been implicated to support anoikis
resistance, however, depending upon the activation, ROS trigger anoikis-inducing cell death [61]. …

[HTML][HTML] Mitochondrial metabolism-mediated redox regulation in cancer progression

AC Boese, S Kang - Redox Biology, 2021 - Elsevier
redox homeostasis, thereby contributing to anoikis susceptibility. Therefore, mitigating oxidative
stress is likely crucial for anoikis resistance … promotes anoikis resistance and survival in …

[HTML][HTML] Manganese superoxide dismutase promotes anoikis resistance and tumor metastasis

S Kamarajugadda, Q Cai, H Chen, S Nayak, J Zhu… - Cell death & …, 2013 - nature.com
… In general, the balance between the production and elimination of ROS leads to homeostasis
Redox regulation of anoikis: reactive oxygen species as essential mediators of cell survival. …

Anoikis resistance: an essential prerequisite for tumor metastasis

YN Kim, KH Koo, JY Sung, UJ Yun… - International journal of …, 2012 - Wiley Online Library
… tissue homeostasis and development. Dysregulation of anoikis, such as anoikis resistance,
… of biomolecules, and maintenance of an appropriate redox status to support cell division, …

Integration of autophagy and anoikis resistance in solid tumors

J Yang, Z Zheng, X Yan, X Li, Z Liu… - The Anatomical …, 2013 - Wiley Online Library
… In addition to metabolic stress, the cellular redox state regulates autophagy both positively
… ROS and autophagy sustains the cellular redox homeostasis and cell survival (Chen et al., …