Dysfunctional and proinflammatory regulatory T-lymphocytes are essential for adverse cardiac remodeling in ischemic cardiomyopathy
… We hypothesized that Tregs are dysfunctional in ischemic cardiomyopathy and HF, and they
… CD4 + T cells, as we have shown cardiac profibrotic effects of splenic CD4 + T cells from …
… CD4 + T cells, as we have shown cardiac profibrotic effects of splenic CD4 + T cells from …
Activated T lymphocytes are essential drivers of pathological remodeling in ischemic heart failure
…, MA Ismahil, M Goel, B Patel, T Hamid… - … : Heart Failure, 2017 - Am Heart Assoc
… regulatory T cells (Tregs) that globally suppress the activation of immune responses. Given
that ischemic … Therefore, we propose that ischemic cardiomyopathy should be thought of, in …
that ischemic … Therefore, we propose that ischemic cardiomyopathy should be thought of, in …
Regulatory T cells in ischemic cardiovascular injury and repair
R Zhuang, MW Feinberg - Journal of Molecular and Cellular Cardiology, 2020 - Elsevier
… Following ischemic injury, immune cells infiltrate tissues and produce inflammatory … to
the development of diverse ischemic diseases including ischemic heart disease (IHD) [1], …
the development of diverse ischemic diseases including ischemic heart disease (IHD) [1], …
The prognostic impact of circulating regulatory T lymphocytes on mortality in patients with ischemic heart failure with reduced ejection fraction
…, L Koller, N Kazem, F Hofer, B Richter… - Mediators of …, 2020 - Wiley Online Library
… regulatory Tregs might have a major impact on the limitation of inflammation-triggered local
tissue damage, cardiac … Therefore, we aimed to investigate the impact of regulatory T cells on …
tissue damage, cardiac … Therefore, we aimed to investigate the impact of regulatory T cells on …
[HTML][HTML] Regulatory T cells in chronic heart failure
Y Lu, N Xia, X Cheng - Frontiers in Immunology, 2021 - frontiersin.org
… , dilated cardiomyopathy (DCM), and ischemic HF (37–40)… ischemic HFrEF patients (42).
Except for the change in Treg number, the suppression function of Tregs on conventional T cells …
Except for the change in Treg number, the suppression function of Tregs on conventional T cells …
[HTML][HTML] Decreased circulating follicular regulatory T cells in patients with dilated cardiomyopathy
X Liu, W Zhang, Z Han - Brazilian Journal of Medical and Biological …, 2021 - SciELO Brasil
… Follicular regulatory T cells (Tfr) have critical functions in … Tfr cell frequency in patients with
dilated cardiomyopathy (DCM)… DCM cases showed markedly reduced Tfr cell rates and Tfr/Tfh …
dilated cardiomyopathy (DCM)… DCM cases showed markedly reduced Tfr cell rates and Tfr/Tfh …
Regulatory Role of CD4+ T Cells in Myocarditis
D Vdovenko, U Eriksson - Journal of immunology research, 2018 - Wiley Online Library
… severity and prevent transition to inflammatory dilated cardiomyopathy. Interestingly, recent
… in myocarditis. These subsets include Th1 and Th17 effector cells and regulatory T cells, …
… in myocarditis. These subsets include Th1 and Th17 effector cells and regulatory T cells, …
A unique population of regulatory T cells in heart potentiates cardiac protection from myocardial infarction
…, N Li, M Liu, J Jiao, Z Zhu, J Li, D Li, T Tang, B Lv… - Circulation, 2020 - Am Heart Assoc
… We demonstrate that regulatory T cells (Tregs) that accumulate in the injured myocardium
after myocardial infarction (MI) or myocardial ischemia/reperfusion injury have a distinct …
after myocardial infarction (MI) or myocardial ischemia/reperfusion injury have a distinct …
[HTML][HTML] Association between regulatory T cells and ischemic heart disease: a Mendelian randomization study
Y Hou, K Si, J Yang, T Liu, B Abdelazeem… - Journal of Thoracic …, 2024 - ncbi.nlm.nih.gov
… of coronary atherosclerosis and the occurrence of ischemic heart disease (IHD). Regulatory
T cells (Tregs) play an essential regulatory role in atherosclerotic plaque formation and …
T cells (Tregs) play an essential regulatory role in atherosclerotic plaque formation and …
Defective Circulating CD4+CD25+Foxp3+CD127low Regulatory T-cells in Patients with Chronic Heart Failure
TT Tang, YJ Ding, YH Liao, X Yu, H Xiao… - Cellular Physiology and …, 2010 - karger.com
… in the pathogenesis of chronic heart failure (CHF). Regulatory T cells appear central to the
… dilated cardiomyopathy (DCM) showed infiltration of T cells and transfer of peripheral blood …
… dilated cardiomyopathy (DCM) showed infiltration of T cells and transfer of peripheral blood …
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