Glycosylation‐based serum biomarkers for cancer diagnostics and prognostics
A Kirwan, M Utratna, ME O'Dwyer… - BioMed research …, 2015 - Wiley Online Library
Cancer is the second most common cause of death in developed countries with
approximately 14 million newly diagnosed individuals and over 6 million cancer‐related …
approximately 14 million newly diagnosed individuals and over 6 million cancer‐related …
The sweet and sour of serological glycoprotein tumor biomarker quantification
Aberrant and dysregulated protein glycosylation is a well-established event in the process of
oncogenesis and cancer progression. Years of study on the glycobiology of cancer have …
oncogenesis and cancer progression. Years of study on the glycobiology of cancer have …
Glycans and glycoproteins as specific biomarkers for cancer
Protein glycosylation and other post-translational modifications are involved in potentially all
aspects of human growth and development. Defective glycosylation has adverse effects on …
aspects of human growth and development. Defective glycosylation has adverse effects on …
Glycomic approaches for the discovery of targets in gastrointestinal cancer
S Mereiter, M Balmaña, J Gomes, A Magalhães… - Frontiers in …, 2016 - frontiersin.org
Gastrointestinal (GI) cancer is the most common group of malignancies and many of its types
are among the most deadly. Various glycoconjugates have been used in clinical practice as …
are among the most deadly. Various glycoconjugates have been used in clinical practice as …
A strategy for discovery of cancer glyco‐biomarkers in serum using newly developed technologies for glycoproteomics
Detection of cancer at early stages that can be treated through surgery is a difficult task. One
methodology for cancer biomarker discovery exploits the fact that glycoproteins produced by …
methodology for cancer biomarker discovery exploits the fact that glycoproteins produced by …
Glycoproteomics‐based identification of cancer biomarkers
EH Kim, DE Misek - International journal of proteomics, 2011 - Wiley Online Library
Protein glycosylation is one of the most common posttranslational modifications in
mammalian cells. It is involved in many biological pathways and molecular functions and is …
mammalian cells. It is involved in many biological pathways and molecular functions and is …
Developments in the identification of glycan biomarkers for the detection of cancer
LR Ruhaak, S Miyamoto, CB Lebrilla - Molecular & Cellular Proteomics, 2013 - ASBMB
Changes in glycosylation readily occur in cancer and other disease states. Thanks to recent
advances in the development of analytical techniques and instrumentation, especially in …
advances in the development of analytical techniques and instrumentation, especially in …
Glycosylation markers in cancer
A Silsirivanit - Advances in clinical chemistry, 2019 - Elsevier
Alteration of glycosylation, a hallmark of cancer, results in the production of tumor-
associated glycans or glycoproteins. These molecules are subsequently secreted or …
associated glycans or glycoproteins. These molecules are subsequently secreted or …
Evaluation of the serum N‐linked glycome for the diagnosis of cancer and chronic inflammation
The identification of serum biomarkers has lead to improvements in the detection and
diagnosis of cancer, and combinations of these biomarkers have increased further their …
diagnosis of cancer, and combinations of these biomarkers have increased further their …
Alterations in glycosylation as biomarkers for cancer detection
Glycoconjugates constitute a major class of biomolecules which include glycoproteins,
glycosphingolipids and proteoglycans. Glycans are involved in several physiological and …
glycosphingolipids and proteoglycans. Glycans are involved in several physiological and …