We describe the isolation and characterization of a novel cDNA encoding a polypeptide that
interacts in a yeast two-hybrid system as well as in mammalian cells with the retinoblastoma …

We have previously isolated cDNA of a novel protein (RBQ-1, HGMW-approved symbol
RBBP6) that binds to the retinoblastoma gene product (pRB). Total nucleotide sequence of …

Background: Antibodies isolated from cancer patients have been used to identify genes
encoding tumor-associated antigen epitopes relevant to immune responses in cancer …

The retinoblastoma protein (Rb) is a target of viral oncoproteins. To explore the hypothesis
that viral proteins may be structural mimics of cellular proteins, we have searched cDNA …

We have previously identified a small-cell lung cancer cell line (NCI-H209) that expresses
an aberrant, underphosphorylated form of the retinoblastoma protein RB1. Molecular …

The identification of the retinoblastoma gene (rb) has sparked intense inves tigation of tumor
suppressor genes. These genes, like oncogenes, can encode transcriptional regulators …

Retinoblastoma protein (Rb) is an important regulator of vertebrate cell cycle and
development. It functions through a direct interaction with protein factors involved in cell …

We have isolated distinct clones for cellular proteins that bind to the retinoblastoma protein
by direct screening of cDNA expression libraries using purified pRB as a probe. The total …

The retinoblastoma gene product is an abundant nuclear protein whose 'pocket
domain'mediates numerous protein–protein interactions. A substantial proportion of the RB …

The subcellular localization of the retinoblastoma (RB) protein has been studied in primate
cell lines by immunofluorescence staining using different monoclonal and polyclonal …