Epigenetics is the study of the regulation of gene activity that is not dependent on nucleotide
sequence; this may include heritable changes in gene activity and expression, but also long …

This multivolume reference work addresses the fact that the well being of humankind is
predicated not only on individuals receiving adequate nutrition but also on their genetic …

DNA is intimately incardinated with histones forming chromatin. Chromatin remodeling
means changes in chromatin structure (ie, histone posttranscriptional modifications) that can …

Publisher Summary This chapter focuses on the metabolic processes involved in one-
carbon (methyl) donor production and their impact on DNA methylation. It discusses the …

Contents 5.1 Introduction............................................................................................ 1055.1. 1 DNA
methylation...................................................................... 106 5.1. 2 DNA methylation for …

Epigenetics can be defined as inheritable and reversible phenomena that affect gene
expression without altering the underlying base pair sequence. Epigenomics is the study of …

Epigenetic changes are inherited alterations in DNA that affect gene expression and
function without altering the DNA sequence. DNA methylation is one epigenetic process …

Although the field of genetics has grown by leaps and bounds within the last decade due to
the completion and availability of the human genome sequence, transcriptional regulation …

The function of one-carbon metabolism is that of regulating the provision of methyl groups
for biological methylation reactions including that of DNA and histone proteins. Methylation …

DNA methylation is an important epigenetic mechanism of transcriptional control. DNA
methylation plays an essential role in maintaining cellular function, and changes in …