In the last few years, the idea of food and nutrition has undergone radical changes. The
paradigm defining food as a simple source of energy and body mass has evolved in a novel …

Epigenetic regulation is central to genome structure and function. Epigenetic status varies
between individuals, and there is increasing awareness of the importance of this variation in …

Methylation of DNA occurs at cytosines within CpG (cytosine-guanine) dinucleotides and is
1 of several epigenetic mechanisms that serve to establish and maintain tissue-specific …

DNA methylation is an enzymatic modification carried out by DNA methyltransferases.
Alterations in DNA methylation patterns are the best understood epigenetic cause of disease …

Metabolism includes anabolism and catabolism, which play an essential role in many
biological processes. Chromatin modifications are post‐translational modifications of …

Epigenetic regulation is a dynamic and reversible process that plays an important role in the
normal development and control of gene expression in vertebrates. However, imbalances in …

The methylation of DNA helps stabilize chromatin in an inactive configuration and inhibits
gene transcription. This mechanism of gene regulation is involved in essential genetic …

Epigenetic changes in chromatin structure can influence gene expression without affecting
the DNA sequence. The most commonly studied epigenetic modification, DNA methylation …

The spatial arrangement and three-dimensional structure of DNA in the nucleus is controlled
through the interdigitation of DNA binding proteins such as histones and their modifiers, the …