Epigenetics refers to changes in chromatin structure that cannot be explained by alterations
in the DNA sequence. Nutrients have the ability to reverse or modify epigenetic events such …

Publisher Summary There is increasing evidence that epigenetic modifications play a crucial
role in determining the dynamic structure and function of chromatin and that the epigenetic …

The five leading causes of cancer-related deaths are lung (1,760,000 deaths), colorectal
(862,000 deaths), stomach (783,000 deaths), liver (782,000 deaths), and breast (627,000 …

Aberrations in function and expression of a wide variety of genes are the hallmarks of cancer
cells. A growing body of evidence shows that these aberrations are affected by genetics and …

Highlights•Epigenetic methylation and acetylation are sensitive to cellular metabolic
status.•Diet and environment conditions shape epigenetics through metabolism.•Stem cells …

Epigenetic events constitute an important mechanism by which gene function is selectively
activated or inactivated. Since epigenetic events are susceptible to change they offer …

5-Methylcytosine (5mC) was first detected in mammalian DNA 60 years ago1 and within six
years, it was demonstrated that the only dinucleotide with significant 5mC content was 5mC …

The inheritance of information based on gene expression levels is known as epigenetics, as
opposed to genetics, which refers to information transmitted on the basis of gene sequence …

DNA methylation is a post-replicative, or epigenetic, modification of the genome that is
critical for proper mammalian embryonic development, gene silencing, X chromosome …

DNA methylation patterns varies with the stage of carcinogenesis by inducing global
hypomethylation in preneoplastic cells and regional hypermethylation in tumor cells (2) …