The transmembrane protein CD33 is a sialic acid-binding immunoglobulin-like lectin that
regulates innate immunity but has no known functions in the brain. We have previously …

Increasing evidence supports a role of the CD40 receptor–CD40 ligand (CD40–CD40L)
interaction in the pathogenesis of Alzheimer's disease (AD). It has previously been shown …

Inflammatory activation of microglia in response to neurodegenerative changes in diseases
such as Alzheimer's disease (AD) and Parkinson's disease has been extensively described …

The scavenger receptor CD36 binds a diverse array of ligands, including thrombospondin-1,
oxidized low density lipoprotein (OxLDL), fatty acids, anionic phospholipids, and apoptotic …

CD36, a class-B scavenger receptor involved in multiple functions, including inflammatory
signaling, may also contribute to ischemic brain injury through yet unidentified mechanisms …

Background and Purpose—Inflammation and hypercoagulability contribute to the
development of acute cerebral ischemia. Both can be mediated by the CD40 system. This …

CD36 is a membrane glycoprotein that is present on various types of cells, including
monocytes, macrophages, microvascular endothelial cells, adipocytes and platelets …

The macrophage scavenger receptor CD36 plays a key role in the initiation of
atherosclerosis through its ability to bind to and internalize oxidized low-density lipoproteins …

Alzheimer's disease (AD) is characterized by the deposition of β-amyloid (Aβ)-containing
plaques within the brain that is accompanied by a robust microglial-mediated inflammatory …

CD36 is a multifunctional membrane receptor present on mononuclear phagocytes,
platelets, and other cells that serves as a scavenger receptor for oxidized phospholipids …