Genome editing is a powerful technology that can efficiently alter the genome of organisms
to achieve targeted modification of endogenous genes and targeted integration of …

Livestock is an essential life commodity in modern agriculture involving breeding and
maintenance. The farming practices have evolved mainly over the last century for …

As a new genetic engineering technology, gene editing can precisely modify the specific
gene sequence of the organism's genome. In the last 10 years, with the rapid development …

Historically, genetic engineering in livestock proved to be challenging. Without stable
embryonic stem cell lines to utilize, somatic cell nuclear transfer (SCNT) had to be employed …

Contents Genome modification at specific loci in livestock species was only achievable by
performing homologous recombination in somatic cells followed by somatic cell nuclear …

Contents In the last decade, the research community has witnessed a blooming of targeted
genome editing tools and applications. Novel programmable DNA nucleases such as zinc …

Accelerated development of novel CRISPR/Cas9-based genome editing techniques
provides a feasible approach to introduce a variety of precise modifications in the …

Humans are sorely over-dependent on livestock for their daily basic need of food in the form
of meat, milk, and eggs. Therefore, genetic engineering and transgenesis provide the …

After induced mutagenesis and transgenesis, genome editing is the next step in the
development of breeding techniques. Genome editing using site-directed nucleases …

Pigs serve as an important agricultural resource and animal model in biomedical studies.
Efficient and precise modification of pig genome by using recently developed gene editing …