Gastrointestinal absorption of capsaicin and dihydrocapsaicin was studied in rats in vivo and
in situ. Rapid absorption of capsaicin or dihydrocapsaicin from stomach and small intestine …

This study was performed to examine the metabolism and absorption of intragastrically
administered capsaicinoids in the anaesthetized rat.[3 H]-dihydrocapsaicin ([3 H]-DHC) and …

The effects of capsaicin and a crude extract of Capsicum on intestinal glucose absorption
have been studied in vitro. Glucose absorption in the rat jejunum was slightly stimulated by …

Results Intravenous administration of capsaicin. Capsaicin levels in tissues 3 and 10 min
after iv injection of 2 mg kg-1 are shown in Table 1. Three minutes after iv administration an …

A new metabolic oxidation pathway of capsaicin (N-[(4-hydroxy-3-methoxyphenyl)-methyl]-8-
methyl-(E)-6-nonenamide), a major pungent and pharmacologically active principle of hot …

Rats were fed by stomach tube with 50 mg/kg BW/day capsaicin (Sigma) or 0.5 gm/kg
BW/day capsicum fruit crude extract for 60 days. The influences of capsaicin or capsicum …

The effect of capsaicin, a pungent ingredient in capsicum fruit, upon gastric acid secretion
and mucosal blood flow was assessed in the anesthetized rat. At each 15 minute interval …

The interaction of capsaicin with microsomal drug-metabolizing systems was assessed to
determine the role that bioactivation of capsaicin may play in the induction of hepatotoxicity …

Capsaicin is a pungent principle of hot red pepper and a non-nutrient. Capsaicin
supplementation to high fat diet prevents fat deposit in the adipose tissue through secretion …

The oral toxicity of capsaicin was investigated in mice and rats. Oral LDSO values were
118.8 mg/kg for male and 97.4 mg/kg for female mice, and 161.2 mg/kg for male and 148.1 …