[HTML][HTML] Iron starvation leads to increased expression of Cu/Zn-superoxide dismutase in Aspergillus
H Oberegger, I Zadra, M Schoeser, H Haas - FEBS letters, 2000 - Elsevier
In a search for iron-regulated proteins of Aspergillus nidulans and Aspergillus fumigatus a
16-kDa protein was identified which is about 5-fold upregulated during iron starvation in …
16-kDa protein was identified which is about 5-fold upregulated during iron starvation in …
Protective role of superoxide dismutase in iron toxicity in yeast
R Wisnicka, A Krzepiłko, J Wawryn, Z Krawiec… - IUBMB …, 1998 - Wiley Online Library
It has been found that yeast mutants deficient in cytosolic superoxide dismutase CuZnSOD
are hypersensitive to ferrous iron. In contrast mutants that are deficient in catalases and …
are hypersensitive to ferrous iron. In contrast mutants that are deficient in catalases and …
Yeast lacking superoxide dismutase (s) show elevated levels of “free iron” as measured by whole cell electron paramagnetic resonance
C Srinivasan, A Liba, JA Imlay, JS Valentine… - Journal of Biological …, 2000 - ASBMB
A current hypothesis explaining the toxicity of superoxide anion in vivo is that it oxidizes
exposed [4Fe-4S] clusters in certain vulnerable enzymes causing release of iron and …
exposed [4Fe-4S] clusters in certain vulnerable enzymes causing release of iron and …
Purification and characterization of Ag, Zn-superoxide dismutase from Saccharomyces cerevisiae exposed to silver.
MR Ciriolo, P Civitareale, MT Carri, A De Martino… - Journal of Biological …, 1994 - Elsevier
Cu, Zn-superoxide dismutase plays an important role in protecting cells from oxygen toxicity
by catalyzing the dismutation of superoxide anion into hydrogen peroxide and oxygen. In …
by catalyzing the dismutation of superoxide anion into hydrogen peroxide and oxygen. In …
Prokaryotic iron superoxide dismutase replaces cytosolic copper, zinc superoxide dismutase in protecting yeast cells against oxidative stress
The iron superoxide dismutase (FeSOD) gene of Escherichia coli was cloned in
Saccharomyces cerevisiae cells deficient in copper, zinc superoxide dismutase (Cu …
Saccharomyces cerevisiae cells deficient in copper, zinc superoxide dismutase (Cu …
[引用][C] Measurement of “free” or electron paramagnetic resonance-detectable iron in whole yeast cells as indicator of superoxide stress
C Srinivasan, EB Gralla - Methods in enzymology, 2002 - Elsevier
Yeast, like most eukaryotes, contain manganese superoxide dismutase (MnSOD; product of
the SOD2 gene) in the mitochondria and copper, zinc superoxide dismutase (Cu, ZnSOD; …
the SOD2 gene) in the mitochondria and copper, zinc superoxide dismutase (Cu, ZnSOD; …
Cu, Zn superoxide dismutase and copper deprivation and toxicity in Saccharomyces cerevisiae
MA Greco, DI Hrab, W Magner… - Journal of bacteriology, 1990 - Am Soc Microbiol
A wild-type strain of the yeast Saccharomyces cerevisiae grown at a medium [Cu] of less
than or equal to 50 nM contained less Cu, Zn superoxide dismutase (SOD) mRNA (60%) …
than or equal to 50 nM contained less Cu, Zn superoxide dismutase (SOD) mRNA (60%) …
The Transcription Factor ZafA Regulates the Homeostatic and Adaptive Response to Zinc Starvation in Aspergillus fumigatus
R Vicentefranqueira, J Amich, L Marín, CI Sánchez… - Genes, 2018 - mdpi.com
One of the most important features that enables Aspergillus fumigatus to grow within a
susceptible individual and to cause disease is its ability to obtain Zn2+ ions from the …
susceptible individual and to cause disease is its ability to obtain Zn2+ ions from the …
The interplay between zinc and iron homeostasis in Aspergillus fumigatus under zinc‐replete conditions relies on the iron‐mediated regulation of alternative transcription units of …
R Vicentefranqueira, F Leal, L Marín… - Environmental …, 2019 - Wiley Online Library
Aspergillus fumigatus is a saprophyte fungus that typically grows on organic decaying matter
but can also parasitize immunosuppressed hosts. This is explained, in part, by its great …
but can also parasitize immunosuppressed hosts. This is explained, in part, by its great …
SREA is involved in regulation of siderophore biosynthesis, utilization and uptake in Aspergillus nidulans
H Oberegger, M Schoeser, I Zadra, B Abt… - Molecular …, 2001 - Wiley Online Library
Under conditions of low iron availability, most fungi excrete siderophores in order to mobilize
extracellular iron. We show that lack of the GATA‐type transcription factor SREA in …
extracellular iron. We show that lack of the GATA‐type transcription factor SREA in …