[HTML][HTML] Iron starvation leads to increased expression of Cu/Zn-superoxide dismutase in Aspergillus

H Oberegger, I Zadra, M Schoeser, H Haas - FEBS letters, 2000 - Elsevier
In a search for iron-regulated proteins of Aspergillus nidulans and Aspergillus fumigatus a
16-kDa protein was identified which is about 5-fold upregulated during iron starvation in …

Protective role of superoxide dismutase in iron toxicity in yeast

R Wisnicka, A Krzepiłko, J Wawryn, Z Krawiec… - IUBMB …, 1998 - Wiley Online Library
It has been found that yeast mutants deficient in cytosolic superoxide dismutase CuZnSOD
are hypersensitive to ferrous iron. In contrast mutants that are deficient in catalases and …

Yeast lacking superoxide dismutase (s) show elevated levels of “free iron” as measured by whole cell electron paramagnetic resonance

C Srinivasan, A Liba, JA Imlay, JS Valentine… - Journal of Biological …, 2000 - ASBMB
A current hypothesis explaining the toxicity of superoxide anion in vivo is that it oxidizes
exposed [4Fe-4S] clusters in certain vulnerable enzymes causing release of iron and …

Purification and characterization of Ag, Zn-superoxide dismutase from Saccharomyces cerevisiae exposed to silver.

MR Ciriolo, P Civitareale, MT Carri, A De Martino… - Journal of Biological …, 1994 - Elsevier
Cu, Zn-superoxide dismutase plays an important role in protecting cells from oxygen toxicity
by catalyzing the dismutation of superoxide anion into hydrogen peroxide and oxygen. In …

Prokaryotic iron superoxide dismutase replaces cytosolic copper, zinc superoxide dismutase in protecting yeast cells against oxidative stress

DR Agius, WH Bannister, R Balzan - IUBMB Life, 1998 - Wiley Online Library
The iron superoxide dismutase (FeSOD) gene of Escherichia coli was cloned in
Saccharomyces cerevisiae cells deficient in copper, zinc superoxide dismutase (Cu …

[引用][C] Measurement of “free” or electron paramagnetic resonance-detectable iron in whole yeast cells as indicator of superoxide stress

C Srinivasan, EB Gralla - Methods in enzymology, 2002 - Elsevier
Yeast, like most eukaryotes, contain manganese superoxide dismutase (MnSOD; product of
the SOD2 gene) in the mitochondria and copper, zinc superoxide dismutase (Cu, ZnSOD; …

Cu, Zn superoxide dismutase and copper deprivation and toxicity in Saccharomyces cerevisiae

MA Greco, DI Hrab, W Magner… - Journal of bacteriology, 1990 - Am Soc Microbiol
A wild-type strain of the yeast Saccharomyces cerevisiae grown at a medium [Cu] of less
than or equal to 50 nM contained less Cu, Zn superoxide dismutase (SOD) mRNA (60%) …

The Transcription Factor ZafA Regulates the Homeostatic and Adaptive Response to Zinc Starvation in Aspergillus fumigatus

R Vicentefranqueira, J Amich, L Marín, CI Sánchez… - Genes, 2018 - mdpi.com
One of the most important features that enables Aspergillus fumigatus to grow within a
susceptible individual and to cause disease is its ability to obtain Zn2+ ions from the …

The interplay between zinc and iron homeostasis in Aspergillus fumigatus under zinc‐replete conditions relies on the iron‐mediated regulation of alternative transcription units of …

R Vicentefranqueira, F Leal, L Marín… - Environmental …, 2019 - Wiley Online Library
Aspergillus fumigatus is a saprophyte fungus that typically grows on organic decaying matter
but can also parasitize immunosuppressed hosts. This is explained, in part, by its great …

SREA is involved in regulation of siderophore biosynthesis, utilization and uptake in Aspergillus nidulans

H Oberegger, M Schoeser, I Zadra, B Abt… - Molecular …, 2001 - Wiley Online Library
Under conditions of low iron availability, most fungi excrete siderophores in order to mobilize
extracellular iron. We show that lack of the GATA‐type transcription factor SREA in …