Acetaminophen (APAP) overdose would lead to liver toxicity and even acute liver failure in
severe cases by triggering an inflammatory response and oxidative stress. Sesamin has …

Sesamin has been described to exert anti-oxidant and anti-inflammatory properties. In
present study, we investigated the potential effects and mechanisms of sesamin on …

Acetaminophen (APAP) is a common antipyretic and analgesic drug, but its overdose can
induce acute liver failure with lack of effective therapies. Hesperetin, a dihydrogen flavonoid …

Acetaminophen (APAP) overdose is one of the most common causes of drug‐induced acute
liver failure in humans. To investigate the hepatoprotective effect of salvianolic acid C (SAC) …

Acetaminophen (APAP) can cause acute liver failure, but treatment options are still limited.
Kahweol is the main diterpene compound of coffee and possesses antioxidant and anti …

Cyclophosphamide, an alkylating agent integral to specific cancer chemotherapy protocols,
is often curtailed in application owing to its significant hepatotoxic side effects. Therefore …

This experiment was to explore the possible defensive properties and potential molecular
mechanisms of Camellia japonica (CJ) against APAP-stimulated acute liver failure (ALF) in …

Background: In this study, we investigated the potential anti-inflammatory and antioxidative
effects of sesamin on acute liver injury. Lead (Pb) causes oxidative damage and enhances …

Acetaminophen (APAP) overdose causes acute liver injury and leads to fatal liver damage.
However, the therapies are quite limited. Shikonin is a natural product with antioxidant and …

Cardamonin (CD), a naturally occurring chalcone derived from the Alpinia species, has
been shown to exert antioxidant and anti-inflammatory activity, but its role in the prevention …