Overdose of acetaminophen (APAP) can cause acute liver injury that is sometimes fatal,
requiring efficient pharmacological intervention. The traditional Chinese herb Bupleurum …

An overdose of the most popular analgesic, acetaminophen (APAP), is one of the leading
causes of acute liver failure. It is well established that glutathione is exhausted by APAP …

Sesamin (Ses), one of the major lignan derived from sesame seeds, has been reported to
have many benefits and medicinal properties. However, its protective effects against carbon …

Acetaminophen (APAP) overdose is the main cause of acute liver failure. Apigenin (API) is a
natural dietary flavonol with high antioxidant capacity. Herein, we investigated protection by …

Background and purpose An overdose of acetaminophen (APAP) causes acute liver
damage and lead to liver failure. Therefore, it is of great clinical significance to find drugs for …

Intestinal ischemia‐reperfusion (I/R) may induce cell/tissue injuries, leading to multiple
organ failure. Based on our preexperiments, we proposed that sesamin could protect …

Acetaminophen (APAP) overdose is the leading cause of acute liver failure (ALF) in the
Western world, with limited treatment opportunities. 3, 5, 7, 4′-Tetrahydroxyflavanone …

An acetaminophen (APAP) overdose induces oxidative stress and acute hepatic injury or
even death. We investigated the prophylactic effect of sesamol (SM) on mitochondrial …

Acetaminophen (APAP) overdose accounts for half of the cases of acute liver failure
worldwide. We previously reported that Sestrin2 (Sesn2) protects against d-galactosamine …

APAP (Acetaminophen)-induced hepatic injury is a major public health threat that requires
continuous searching for new effective therapeutics. KSG (Kaempferol-3-sophoroside-7 …