The monitoring of minimal residual disease (MRD) through low sensitivity real-time (RT)
polymerase chain reaction (PCR) analysis of BCR-ABL transcripts allows early detection of …

BACKGROUND AND OBJECTIVES: The most common translocation in chronic myeloid
leukemia (CML) t (9; 22)(q34; q22) produces the BCR/ABL fusion gene. We set up and …

Quantitative competitive RT-PCR techniques have been developed to detect BCR-ABL
fusion transcripts in CML but they are hardly reproducible. In this work, we have developed …

We prospectively studied 98 chronic myeloid leukemia (CML) patients after bone marrow
transplantation by competitive polymerase chain reaction to detect and quantify leukemia …

Relapse of chronic myelogenous leukemia after bone marrow transplantation can be
detected by using clinical, cytogenetic, or molecular tools. A modification of the polymerase …

Patients with CML post allogeneic BMT or during treatment with Interferon were monitored in
bone marrow and peripheral blood for BCR-ABL transcripts by RT-PCR and in the majority …

Methods of minimal residual disease (MRD) detection in chronic myelogenous leukemia
(CML) include chromosome analysis, reverse transcriptase polymerase chain reaction (RT …

We report here the results of polymerase chain reaction (PCR) for bcr-abl transcript and
clinical details derived from 64 chronic myelogenous leukemia (CML) patients after …

We have used a new single‐step real‐time reverse transcription polymerase chain reaction
(RT‐PCR) method to quantify BCR‐ABL transcripts, thereby estimating the relapse stage in …

A substantial minority of patients with chronic myeloid leukaemia (CML) achieve a complete
response to treatment with interferon‐α (IFN‐α), defined as the disappearance of …