Epidermal growth factor receptor (EGFR) has fundamental roles in normal physiology and
cancer, making it a rational target for cancer therapy. Surprisingly, however, inhibitors that …

Abstract Epidermal Growth Factor Receptor (EGFR) enacts major roles in the maintenance
of epithelial tissues. However, when EGFR signaling is altered, it becomes the grand …

The epidermal growth factor receptor (EGFR) pathway is one of the most dysregulated
molecular pathways in human cancers. Despite its well-established importance in tumor …

The physiological function of the epidermal growth factor receptor (EGFR) is to regulate
epithelial tissue development and homeostasis. In pathological settings, mostly in lung and …

Signaling from the epidermal growth factor receptor (EGFR) elicits multiple biological
responses, including cell proliferation, migration, and survival. Receptor endocytosis and …

The epidermal growth factor receptor (ErbB1 or EGFR) has been found to be altered in a
variety of human cancers. A number of agents targeting these receptors, including specific …

The ligand-stimulated epidermal growth factor receptor (EGFR) has been extensively
studied in the analysis of molecular mechanisms regulating endocytic traffic and the role of …

Epidermal growth factor receptor (EGFR) signaling inhibition represents a highly promising
arena for the application of molecularly targeted cancer therapies. Evolving from several …

The epidermal growth factor receptor (EGFR) frequently associates with cancer and already
serves as a target for therapy. We report that inflammatory cytokines and ultraviolet (UV) …

Both the epidermal growth factor receptor (EGFR) and the insulin-like growth factor-1
receptor (IGF-1R) can contribute to tumor development and-progression through their effects …