The role of particulate pollutants in pulmonary inflammation and asthma: evidence for the involvement of organic chemicals and oxidative stress

AE Nel, D Diaz-Sanchez, N Li - Current opinion in pulmonary …, 2001 - journals.lww.com
We review the literature indicating that the adverse health effects of ambient particulate
matter involve the generation of oxidative stress and inflammation, as well as …

Particulate air pollutants and asthma: a paradigm for the role of oxidative stress in PM-induced adverse health effects

N Li, M Hao, RF Phalen, WC Hinds, AE Nel - Clinical immunology, 2003 - Elsevier
Asthma is a chronic inflammatory disease, which involves a variety of different mediators,
including reactive oxygen species. There is growing awareness that particulate pollutants …

[PDF][PDF] The role of reactive oxygen species and oxidative stress in mediating particulate matter injury

T Xia, M Kovochich, A Nel - Clin Occup Environ Med, 2006 - academia.edu
Several plausible mechanisms have been proposed to explain the adverse health effects of
particulate matter (PM) in polluted ambient air [1]. To date, experimental support has been …

Enhancement of allergic inflammation by diesel exhaust particles: permissive role of reactive oxygen species

AM Casillas, T Hiura, N Li, AE Nel - Annals of Allergy, Asthma & …, 1999 - Elsevier
BACKGROUND: Diesel emission particulates (DEP) exert effects on the immune system and
act as an adjuvant which enhances allergic inflammation. Animal and human models have …

Reactive oxygen species in pulmonary inflammation by ambient particulates

F Tao, B Gonzalez-Flecha, L Kobzik - Free Radical Biology and Medicine, 2003 - Elsevier
Exposure to ambient air pollution particles (PM) has been associated with increased
cardiopulmonary morbidity and mortality, particularly in individuals with pre-existing disease …

The role of oxidative stress in ambient particulate matter-induced lung diseases and its implications in the toxicity of engineered nanoparticles

N Li, T Xia, AE Nel - Free radical biology and medicine, 2008 - Elsevier
Ambient particulate matter (PM) is an environmental factor that has been associated with
increased respiratory morbidity and mortality. The major effect of ambient PM on the …

[HTML][HTML] Mechanistic impact of outdoor air pollution on asthma and allergic diseases

SK Huang, Q Zhang, Z Qiu, KF Chung - Journal of thoracic disease, 2015 - ncbi.nlm.nih.gov
Over the past decades, asthma and allergic diseases, such as allergic rhinitis and eczema,
have become increasingly common, but the reason for this increased prevalence is still …

Diesel exhausts particles: Their role in increasing the incidence of asthma. Reviewing the evidence of a causal link

X Muñoz, E Barreiro, V Bustamante… - Science of the Total …, 2019 - Elsevier
Exposure to air pollutants has been correlated with an increase in the severity of asthma and
in the exacerbation of pre-existing asthma. However, whether or not environmental pollution …

Comparison of the pro-oxidative and proinflammatory effects of organic diesel exhaust particle chemicals in bronchial epithelial cells and macrophages

N Li, M Wang, TD Oberley, JM Sempf… - The Journal of …, 2002 - journals.aai.org
Inhaled diesel exhaust particles (DEP) exert proinflammatory effects in the respiratory tract.
This effect is related to the particle content of redox cycling chemicals and is involved in the …

Insights in particulate matter‐induced allergic airway inflammation: focus on the epithelium

KC De Grove, S Provoost, GG Brusselle… - Clinical & …, 2018 - Wiley Online Library
Outdoor air pollution is a major environmental health problem throughout the world. In
particular, exposure to particulate matter (PM) has been associated with the development …