Immunohistochemical studies on the effect of capsaicin on spinal and medullary peptide and monoamine neurons using antisera to substance P, gastrin/CCK …

G Jancsó, T Hökfelt, JM Lundberg, E Kiraly… - Journal of …, 1981 - Springer
After neonatal treatment of rats with capsaicin, the spinal cord, the spinal trigeminal nucleus
and spinal and trigeminal ganglia were analysed with immunohistochemistry using antisera …

Dose-dependent effects of capsaicin on primary sensory neurons in the neonatal rat

JI Nagy, LL Iversen, M Goedert… - Journal of …, 1983 - Soc Neuroscience
The numbers of myelinated and unmyelinated fibers were counted in dorsal roots of adult
rats treated neonatally with capsaicin in doses ranging from 5 to 100 mg/kg. Substance P …

Capsaicin depletes CCK-like immunoreactivity detected by immunohistochemistry, but not that measured by radioimmunoassay in rat dorsal spinal cord

M Schultzberg, GJ Dockray, RG Williams - Brain Research, 1982 - Elsevier
In rats treated neonatally with capsaicin there were significant reductions in substance P
measured by radioimmunoassay in dorsal spinal cord, spinal ganglia, and coelic ganglia …

Neurotoxic action of capsaicin on spinal substance P neurons

JI Nagy, SR Vincent, WMA Staines, HC Fibinger… - Brain research, 1980 - Elsevier
The effect of capsaicin injections into neenatal rats on the ultrastructure of the neonatal
dorsal horn and on some biochemical and behavioral parameters in the adult were …

Capsaicin and sensory neurones—a review

M Fitzgerald - Pain, 1983 - Elsevier
In the late fifties and sixties Jancso published a series of papers on 'the peculiar
pharmacological effect of capsaicin Capsaicin or 8-methyl-N-vanillyi-6-nonenamide is the …

Mechanism of action of capsaicin-like molecules on sensory neurons

A Dray - Life sciences, 1992 - Elsevier
Capsaicin produces pain by selectively activating polymodal nociceptive neurons. This
involves a membrane depolarization and the opening of a unique, cation-selective, ion …

Characterization of the peptide and sensory neurotoxic effects of capsaicin in the guinea pig

SH Buck, JH Walsh, TP Davis, MR Brown… - Journal of …, 1983 - Soc Neuroscience
The effects of capsaicin, the major pungent ingredient of hot peppers, were assessed on
sensory neuron neuropeptide levels and on sensory function in the adult guinea pig …

Neuropharmacological mechanisms of capsaicin and related substances.

A Dray - Biochemical pharmacology, 1992 - europepmc.org
Capsaicin activates poorly myelinated primary afferent neurons, many of which are
polymodal nociceptors. Activation is accompanied by membrane depolarization and the …

Capsaicin's action on the nervous system

JI Nagy - Trends in Neurosciences, 1982 - cell.com
Over the past several decades capsaicin, a natural product of certain species of red pepper,
has been found to have a broad range of physiological effects in adult animals. Recent …

Substance P immunoreactive neurons following neonatal administration of capsaicin

AC Cuello, R Gamse, P Holzer, F Lembeck - … -Schmiedeberg's Archives of …, 1981 - Springer
Neonatal administration of capsaicin on the days 2, 10 or 20 leads to a long-lasting loss of
substance P immunoreactive material in fibers of primary sensory neurons in the spinal cord …