Does activation of midbrain dopamine neurons promote or reduce feeding?
L Boekhoudt, TJM Roelofs, JW De Jong… - International Journal of …, 2017 - nature.com
Background: Dopamine (DA) signalling in the brain is necessary for feeding behaviour, and
alterations in the DA system have been linked to obesity. However, the precise role of DA in …
alterations in the DA system have been linked to obesity. However, the precise role of DA in …
[HTML][HTML] Dopamine signaling in food addiction: role of dopamine D2 receptors
JH Baik - BMB reports, 2013 - ncbi.nlm.nih.gov
Dopamine (DA) regulates emotional and motivational behavior through the mesolimbic
dopaminergic pathway. Changes in DA signaling in mesolimbic neurotransmission are …
dopaminergic pathway. Changes in DA signaling in mesolimbic neurotransmission are …
Dopamine and diet-induced obesity
AG DiFeliceantonio, DM Small - Nature Neuroscience, 2019 - nature.com
In 2010, Johnson and Kenny provided conclusive evidence that extended access to a
Western-style diet promotes addictive-like behavior in rats by downregulating D2 receptors …
Western-style diet promotes addictive-like behavior in rats by downregulating D2 receptors …
Mesolimbic dopamine and its neuromodulators in obesity and binge eating
L Naef, KA Pitman, SL Borgland - CNS spectrums, 2015 - cambridge.org
Obesity has reached epidemic prevalence, and much research has focused on homeostatic
and nonhomeostatic mechanisms underlying overconsumption of food. Mesocorticolimbic …
and nonhomeostatic mechanisms underlying overconsumption of food. Mesocorticolimbic …
Lost in translation? On the need for convergence in animal and human studies on the role of dopamine in diet-induced obesity
LK Janssen, N Herzog, M Waltmann, N Breuer… - Current addiction …, 2019 - Springer
Abstract Purpose of Review Animal and human studies suggest that diet-induced obesity
and plasticity in the central dopaminergic system are linked. However, it is unclear whether …
and plasticity in the central dopaminergic system are linked. However, it is unclear whether …
[HTML][HTML] Dopamine D1 receptor signalling in the lateral shell of the nucleus accumbens controls dietary fat intake in male rats
A Joshi, T Kool, C Diepenbroek, LL Koekkoek… - Appetite, 2021 - Elsevier
Central dopamine signaling regulates reward-related aspects of feeding behavior, and
during diet-induced obesity dopamine receptor signaling is altered. Yet, the influence of …
during diet-induced obesity dopamine receptor signaling is altered. Yet, the influence of …
A putative loop connection between VTA dopamine neurons and nucleus accumbens encodes positive valence to compensate for hunger
X Cui, Q Tong, H Xu, C Xie, L Xiao - Progress in Neurobiology, 2023 - Elsevier
Dopamine (DA) signal play pivotal roles in regulating motivated behaviors, including feeding
behavior, but the role of midbrain DA neurons in modulating food intake and neural circuitry …
behavior, but the role of midbrain DA neurons in modulating food intake and neural circuitry …
Imaging of brain dopamine pathways: implications for understanding obesity
Obesity is typically associated with abnormal eating behaviors. Brain imaging studies in
humans implicate the involvement of dopamine (DA)-modulated circuits in pathologic eating …
humans implicate the involvement of dopamine (DA)-modulated circuits in pathologic eating …
High-fat diet induced adiposity in mice with targeted disruption of the dopamine-3 receptor gene
Dopamine (DA) signaling has been implicated in the control of energy balance and
ingestive behavior. In the present study, we sought to characterize body weight, body fat and …
ingestive behavior. In the present study, we sought to characterize body weight, body fat and …
Striatal dopamine D2 receptors regulate cost sensitivity and behavioral thrift
The role of the dopamine D2 receptor (D2R) in regulating appetitive behavior continues to
be controversial. Earlier literature suggests that reduced D2R signaling diminishes …
be controversial. Earlier literature suggests that reduced D2R signaling diminishes …