There is species divergence in control of DNA methylation during preimplantation
development. The exact pattern of methylation in the bovine embryo has not been …

In mammals, active demethylation of cytosine methylation in the sperm genome prior to
forming a functional zygotic nucleus is thought to be a function of the oocyte cytoplasm …

DNA demethylation and remethylation are crucial for reprogramming of the differentiated
parental/somatic genome in the recipient ooplasm upon somatic cell nuclear transfer. Here …

In studies of somatic cell nuclear transfer (SCNT), the ability of factors within the oocyte to
epigenetically reprogram transferred nuclei is essential for embryonic development of the …

Active demethylation of the paternal genome but not of the maternal genome occurs in
fertilized mouse, rat, pig, and bovine zygotes. To study whether this early demethylation …

Global reduction of DNA methylation, a part of genome reprogramming processes, occurs in
a gradual manner until before implantation and is recognized as a conserved process in …

Alterations to DNA methylation have been attributed to in vitro culture and may affect normal
embryo development. We chose to analyze DNA methylation reprogramming in the rabbit …

Most mouse embryos developing in the absence of the oocyte-derived DNA
methyltransferase 1o (DNMT1o-deficient embryos) have significant delays in development …

In mammals, active demethylation of sperm pronuclear DNA shortly after fertilisation is
thought to be important for reprogramming subsequent embryonic development [1–3]. A …

Mammalian preimplantation development is a critical stage for establishment of the genomic
methylation pattern and proper function of the enzymes responsible for this appear essential …