To analyze the potential mechanisms by which hypoxanthine and adenosine maintain
meiotic arrest in mouse oocytes this study focused on:(1) the uptake and metabolism of …

Oxygen concentration during in vitro culture has a significant effect on the physiology of
embryos, altering metabolic profile and developmental outcome. Although atmospheric …

Cyclic AMP signaling is involved in most aspects of differentiation and maturation of the
granulosa cells in the ovarian follicle. As the genetic programs activated at different stages of …

To determine the effects of adenosine on follicle-stimulating hormone (FSH)-induced
differentiation, granulosa cells isolated from the ovaries of diethylstilbestrol-treated immature …

Trophoblastic cells were separated and cultured from human first trimester and term
placentae for studies on energy metabolism. Changes in the catabolism of prelabeled …

Adenosine has been shown to acutely amplify LH-dependent events in luteal cells and FSH-
dependent events in granulosa cells. In this study, the specificity of purines on mature rat …

Sertoli cell maturation is a complex process involving both morphological and biochemical
changes. These cells have previously been shown to be targets for extracellular purine …

The factors and processes involved in primate follicular development are complex and not
fully understood. An encapsulated three-dimensional (3D) follicle culture system could be a …

To date we have yet to examine whether amino acid (AA) transport in human ovarian
follicles is affected by competitive inhibition. In contrast, transplacental transfer of AAs in late …

Progression of preantral follicle development is essential to further follicle maturation and
ovulation, but there are few models for studying the regulation of preantral follicle survival …