Retinoblastoma protein regulation by the COP9 signalosome
Z Ullah, MS Buckley, DN Arnosti… - Molecular biology of the …, 2007 - Am Soc Cell Biol
Similar to their human counterparts, the Drosophila Rbf1 and Rbf2 Retinoblastoma family
members control cell cycle and developmentally regulated gene expression. Increasing …
members control cell cycle and developmentally regulated gene expression. Increasing …
Diversification of retinoblastoma protein function associated with cis and trans adaptations
Retinoblastoma proteins are eukaryotic transcriptional corepressors that play central roles in
cell cycle control, among other functions. Although most metazoan genomes encode a …
cell cycle control, among other functions. Although most metazoan genomes encode a …
Evidence for Autoregulation and Cell Signaling Pathway Regulation From Genome-Wide Binding of the Drosophila Retinoblastoma Protein
The retinoblastoma (RB) tumor suppressor protein is a transcriptional cofactor with essential
roles in cell cycle and development. Physical and functional targets of RB and its paralogs …
roles in cell cycle and development. Physical and functional targets of RB and its paralogs …
Integrated stability and activity control of the Drosophila Rbf1 retinoblastoma protein
The retinoblastoma (RB) family transcriptional corepressors regulate diverse cellular events
including cell cycle, senescence, and differentiation. The activity and stability of these …
including cell cycle, senescence, and differentiation. The activity and stability of these …
Paradoxical instability–activity relationship defines a novel regulatory pathway for retinoblastoma proteins
The Retinoblastoma (RB) transcriptional corepressor and related family of pocket proteins
play central roles in cell cycle control and development, and the regulatory networks …
play central roles in cell cycle control and development, and the regulatory networks …
Distinct developmental expression of Drosophila retinoblastoma factors
SA Keller, Z Ullah, MS Buckley, RW Henry… - Gene expression …, 2005 - Elsevier
Retinoblastoma (RB) tumor suppressor proteins are important regulators of the cell cycle
and are implicated in a wide variety of human tumors. Genetic analysis of RB mutations in …
and are implicated in a wide variety of human tumors. Genetic analysis of RB mutations in …
Ubiquitination of retinoblastoma family protein 1 potentiates gene-specific repression function
The retinoblastoma (RB) tumor suppressor family functions as a regulatory node governing
cell cycle progression, differentiation, and apoptosis. Post-translational modifications play a …
cell cycle progression, differentiation, and apoptosis. Post-translational modifications play a …
The Drosophila RetinoblastomaBinding Protein 6 Family Member Has Two Isoformsand Is Potentially Involved in Embryonic Patterning
R Hull, B Oosthuysen, UF Cajee, L Mokgohloa… - International journal of …, 2015 - mdpi.com
The human retinoblastoma binding protein 6 (RBBP6) is implicated in esophageal, lung,
hepatocellular and colon cancers. Furthermore, RBBP6 was identified as a strong marker for …
hepatocellular and colon cancers. Furthermore, RBBP6 was identified as a strong marker for …
Rb deficiency during Drosophila eye development deregulates EMC, causing defects in the development of photoreceptors and cone cells
MK Popova, W He, M Korenjak… - Journal of cell …, 2011 - journals.biologists.com
Retinoblastoma tumor suppressor protein (pRb) regulates various biological processes
during development and tumorigenesis. Although the molecular mechanism by which pRb …
during development and tumorigenesis. Although the molecular mechanism by which pRb …
The evolutionarily conserved C-terminal domains in the mammalian retinoblastoma tumor suppressor family serve as dual regulators of protein stability and …
S Sengupta, R Lingnurkar, TS Carey… - Journal of Biological …, 2015 - ASBMB
The retinoblastoma (RB) tumor suppressor and related family of proteins play critical roles in
development through their regulation of genes involved in cell fate. Multiple regulatory …
development through their regulation of genes involved in cell fate. Multiple regulatory …