The prevalence and prognostic value of BRAF mutation in thyroid cancer

E Kebebew, J Weng, J Bauer, G Ranvier… - Annals of …, 2007 - journals.lww.com
Objective: To examine the prevalence of BRAF mutation among thyroid cancer histologic
subtypes and determine the association of BRAF mutation with indicators of poor prognosis …

Higher rate of BRAF mutation in papillary thyroid cancer over time A single‐institution study

A Mathur, W Moses, R Rahbari, E Khanafshar… - Cancer, 2011 - Wiley Online Library
BACKGROUND: The incidence of thyroid cancer has doubled over the past decade. The
reason for this dramatic increase in incidence is controversial. Some investigators have …

Clinicopathologic Implications of the BRAFV600E Mutation in Papillary Thyroid Cancer: A Subgroup Analysis of 3130 Cases in a Single Center

JY Lim, SW Hong, YS Lee, BW Kim, CS Park… - Thyroid, 2013 - liebertpub.com
Background: The BRAF mutation has been shown to be associated with aggressive
clinicopathologic characteristics of papillary thyroid cancer (PTC). However, several studies …

BRAFV600E Mutation is Associated with Tumor Aggressiveness in Papillary Thyroid Cancer

S Kim, KE Lee, JP Myong, J Park, YK Jeon… - World journal of …, 2012 - Springer
Abstract Background The BRAF V600E mutation is the most common genetic alteration
found in papillary thyroid cancer (PTC). Recent studies show that this mutation occurs more …

BRAF mutation predicts a poorer clinical prognosis for papillary thyroid cancer

M Xing, WH Westra, RP Tufano, Y Cohen… - The Journal of …, 2005 - academic.oup.com
Context: Use of BRAF mutation in papillary thyroid cancer (PTC) has the potential to improve
risk stratification of this cancer. Objective: The objective of the study was to investigate the …

Association of BRAF V600E mutation with poor clinicopathological outcomes in 500 consecutive cases of papillary thyroid carcinoma

C Lupi, R Giannini, C Ugolini, A Proietti… - The Journal of …, 2007 - academic.oup.com
Context: Because very few studies have examined the correlation between BRAF mutations
and clinicopathological features of papillary thyroid carcinoma (PTC), we analyzed here a …

Optimizing surgical treatment of papillary thyroid carcinoma associated with BRAF mutation

L Yip, MN Nikiforova, SE Carty, JH Yim, MT Stang… - Surgery, 2009 - Elsevier
BACKGROUND: To date, a mutation of the BRAF oncogene is the most common genetic
alteration found in papillary thyroid carcinoma (PTC) and is associated with extrathyroidal …

Association Between BRAF V600E Mutation and Recurrence of Papillary Thyroid Cancer

M Xing, AS Alzahrani, KA Carson, YK Shong… - Journal of clinical …, 2015 - ascopubs.org
Purpose To investigate the prognostic value of BRAF V600E mutation for the recurrence of
papillary thyroid cancer (PTC). Patients and Methods This was a retrospective multicenter …

BRAF mutation in papillary thyroid carcinoma in a Japanese population: its lack of correlation with high-risk clinicopathological features and disease-free survival of …

Y Ito, H Yoshida, R Maruo, S Morita, T Takano… - Endocrine …, 2009 - jstage.jst.go.jp
Recent studies have demonstrated that BRAFV600E mutation is a common event in
papillary thyroid carcinoma and a majority of these lesions have shown a direct relationship …

Lymphatic mapping establishes the role of BRAF gene mutation in papillary thyroid carcinoma

J Kim, AE Giuliano, RR Turner, RE Gaffney… - Annals of …, 2006 - journals.lww.com
Objective: To define the role of BRAF gene mutation in the progression of papillary thyroid
carcinoma. Summary Background Data: BRAF gene mutation is frequently detected in …