What tangled web: barriers to rampant horizontal gene transfer

CG Kurland - Bioessays, 2005 - Wiley Online Library
Abstract Dawkins in his The Selfish Gene (1) quite aptly applies the term “selfish” to parasitic
repetitive DNA sequences endemic to eukaryotic genomes, especially vertebrates. Doolittle …

On the need for widespread horizontal gene transfers under genome size constraint

H Isambert, RR Stein - Biology direct, 2009 - Springer
Background While eukaryotes primarily evolve by duplication-divergence expansion (and
reduction) of their own gene repertoire with only rare horizontal gene transfers, prokaryotes …

The role of the environment in horizontal gene transfer

H Acar Kirit, JP Bollback… - Molecular Biology and …, 2022 - academic.oup.com
Gene-by-environment interactions play a crucial role in horizontal gene transfer by affecting
how the transferred genes alter host fitness. However, how the environment modulates the …

The role of selfish genetic elements in eukaryotic evolution

GDD Hurst, JH Werren - Nature Reviews Genetics, 2001 - nature.com
Abstract'Selfish genetic elements', such as transposons, homing endonucleases, meiotic
drive chromosomes and heritable microorganisms, are common features of eukaryotes …

Selfish genetic elements

JA Ågren, AG Clark - PLoS genetics, 2018 - journals.plos.org
Selfish genetic elements (historically also referred to as selfish genes, ultra-selfish genes,
selfish DNA, parasitic DNA, genomic outlaws) are genetic segments that can enhance their …

Genome-wide experimental determination of barriers to horizontal gene transfer

R Sorek, Y Zhu, CJ Creevey, MP Francino, P Bork… - Science, 2007 - science.org
Horizontal gene transfer, in which genetic material is transferred from the genome of one
organism to that of another, has been investigated in microbial species mainly through …

Selfish genes, the phenotype paradigm and genome evolution

WF Doolittle, C Sapienza - Nature, 1980 - nature.com
Natural selection operating within genomes will inevitably result in the appearance of DNAs
with no phenotypic expression whose only 'function'is survival within genomes. Prokaryotic …

Horizontal gene transfer: A new taxonomic principle?

L Olendzenski, O Zhaxybayeva, JP Gogarten - Horizontal gene transfer, 2002 - Elsevier
Publisher Summary The important role of horizontal gene transfer (HGT) in the spread of
antibiotic resistance, the formation of pathogenicity islands, and selfish genes has long been …

High expression hampers horizontal gene transfer

C Park, J Zhang - Genome biology and evolution, 2012 - academic.oup.com
Horizontal gene transfer (HGT), the movement of genetic material from one species to
another, is a common phenomenon in prokaryotic evolution. Although the rate of HGT is …

Inevitability of genetic parasites

J Iranzo, P Puigbò, AE Lobkovsky… - Genome biology and …, 2016 - academic.oup.com
Almost all cellular life forms are hosts to diverse genetic parasites with various levels of
autonomy including plasmids, transposons and viruses. Theoretical modeling of the …