Factors that affect the efficacy of inhaled corticosteroids for infants and young children

I Amirav, MT Newhouse, S Minocchieri… - Journal of Allergy and …, 2010 - Elsevier
Infants (0–1 years of age) and young children (1–3 years of age) are a unique
subpopulation with regard to inhaled therapies. There are various anatomic, physiological …

[HTML][HTML] Breathing easier: Addressing the challenges of aerosolizing medications to infants and preschoolers

JL Goralski, SD Davis - Respiratory Medicine, 2014 - Elsevier
An increasing number of patients are dependent on aerosolized therapy to manage
pulmonary diseases, including asthma, cystic fibrosis, and pulmonary arterial hypertension …

Skin reactions to inhaled corticosteroids: incidence, avoidance and management

M Isaksson - Drug safety, 2001 - Springer
Corticosteroids intended for inhalation into the lungs or into the nose have been used since
the 1970s. Only 2 attempts to assess contact allergy attributable to inhaled corticosteroids in …

Variation in pediatric aerosol delivery: importance of facemask

GC Smaldone, E Berg, K Nikander - Journal of aerosol medicine, 2005 - liebertpub.com
We have quantified in vitro the influence of the facemask on the amount of drug delivered
(eg, inhaled mass) by jet nebulizer and pressurized metered dose inhaler (pMDI) valved …

Inhaled corticosteroids: Ocular safety and the hypothalamic-pituitary-adrenal axis

WW Carr, SJ Szefler - Annals of Allergy, Asthma & Immunology, 2016 - Elsevier
Abstract Background Inhaled corticosteroids (ICSs) effectively deliver corticosteroids to
target sites in the lungs and reduce systemic effects compared with oral corticosteroids, but …

Pediatric aerosol therapy: new devices and new drugs

BK Rubin - Respiratory Care, 2011 - rc.rcjournal.com
The lung and conducting airways are ideal portals for drug delivery. The airways are easily
accessible by oral or nasal inhalation; the airway and alveolar surface is large, allowing for …

Aerosol characterization of nebulized intranasal glucocorticoid formulations

A Berlinski, JC Waldrep - Journal of aerosol medicine, 2001 - liebertpub.com
Inhaled glucocorticoids (GCs) are the mainstay of long-term therapy for asthma. The lack of
suitable preparations in the United States has induced clinicians to use intranasal (IN) GC …

Optimal aerosol delivery

ME Levin - Current Allergy & Clinical Immunology, 2011 - journals.co.za
Pressurised metered-dose inhalers (pMDIs), nebulisers and dry-powder inhalers (DPIs) aim
to deliver aerosols to the lungs. With optimal technique, lung deposition ranges from below …

Numerical investigation of aerosol deposition at the eyes when using a hood inhaler for infants—a 3D simulation

I Amirav, T Shakked, DM Broday… - Journal of aerosol …, 2008 - liebertpub.com
A numerical investigation of a hood inhaler is presented, aiming at the assessment of the
amount of aerosol that reaches the eyes of the patient when administrating medications with …

[HTML][HTML] Aerosols how dangerous they are in clinical practice

A Sawhney, S Venugopal, GRJ Babu… - Journal of clinical and …, 2015 - ncbi.nlm.nih.gov
Materials and Methods Subjects for the study were selected from the outpatient Department
of Periodontics, Sri Siddhartha Dental College and Hospital, Tumkur, India. Total 60 patients …