Background Commercial extracts used for diagnosis and treatment of allergy are currently
prepared from natural allergen sources. The aim of this study was to analyse birch pollen …

Background Type I allergy represents a severe health problem in industrialized countries
where up to 20% of the population suffer froin allergic rhinitis, conjunctivitis and allergic …

Bet v 1, the single major allergen from birch pollen, shares IgE epitopes with all major tree
pollen allergens from closely related species such as alder, hazel, hornbeam, beech, and …

Background: Birch pollen is a significant cause of immediate hypersensitivity among
susceptible subjects in temperate climates, affecting 5–54% of the population in western …

Background: Birch pollen is the major allergen in pollinosis in northern Japan. IgE reactivity
to individual birch pollen allergens has been shown to differ between populations of birch …

Background: More than 95% of birch pollen–allergic subjects react with the major birch
pollen allergen, Bet v 1, and almost 60% of them are sensitized exclusively to this allergen …

Background: Sensitivity to birch pollen allergens is a common feature among European
patients with seasonal pollen allergy. In this in vitro study, we examined the specific serum …

Two monoclonal antibodies against birch pollen proteins were produced by immunizing
BALB/c mice with birch pollen extract. In immunoblotting experiments, antibody BIP 1 …

Background Diagnostic procedures using natural extracts show only limited quantitative
correlation between in vivo and in vitro results. Highly pure recombinant allergens might …

Birch belongs to the order Fagales and the family Betulaceae. Birch pollen is one of the most
important airborne inhaled allergens in the north temperate zone, leading to allergic rhinitis …