Predicting diagnostic gene biomarkers associated with immune checkpoints, N6-methyladenosine, and ferroptosis in patients with acute myocardial infarction

X Tong, X Zhao, X Dang, Y Kou, J Kou - Frontiers in cardiovascular …, 2022 - frontiersin.org
This study aimed to determine early diagnosis genes of acute myocardial infarction (AMI)
and then validate their association with ferroptosis, immune checkpoints, and N6 …

Potential diagnostic biomarkers: 6 cuproptosis-and ferroptosis-related genes linking immune infiltration in acute myocardial infarction

M Miao, S Cao, Y Tian, D Liu, L Chen, Q Chai… - Genes & …, 2023 - nature.com
The current diagnostic biomarkers of acute myocardial infarction (AMI), troponins, lack
specificity and exist as false positives in other non-cardiac diseases. Previous studies …

Machine learning revealed ferroptosis features and a novel ferroptosis-based classification for diagnosis in acute myocardial infarction

D Huang, S Zheng, Z Liu, K Zhu, H Zhi, G Ma - Frontiers in Genetics, 2022 - frontiersin.org
Acute myocardial infarction (AMI) is a leading cause of death and disability worldwide. Early
diagnosis of AMI and interventional treatment can significantly reduce myocardial damage …

[HTML][HTML] Development and validation of a random forest diagnostic model of acute myocardial infarction based on ferroptosis-related genes in circulating endothelial …

C Yifan, S Jianfeng, P Jun - Frontiers in Cardiovascular Medicine, 2021 - frontiersin.org
The high incidence and mortality of acute myocardial infarction (MI) drastically threaten
human life and health. In the past few decades, the rise of reperfusion therapy has …

[HTML][HTML] Expression pattern and diagnostic value of ferroptosis-related genes in acute myocardial infarction

J Wu, H Cai, Z Lei, C Li, Y Hu, T Zhang… - Frontiers in …, 2022 - frontiersin.org
Background Ferroptosis is a form of regulatory cell death (RCD) caused by iron-dependent
lipid peroxidation. The role of ferroptosis in the process of acute myocardial infarction (AMI) …

[HTML][HTML] Predicting diagnostic gene biomarkers associated with immune infiltration in patients with acute myocardial infarction

E Zhao, H Xie, Y Zhang - Frontiers in Cardiovascular Medicine, 2020 - frontiersin.org
Objective: The present study was designed to identify potential diagnostic markers for acute
myocardial infarction (AMI) and determine the significance of immune cell infiltration in this …

Uncovering potential diagnostic biomarkers of acute myocardial infarction based on machine learning and analyzing its relationship with immune cells

L Kang, Q Zhao, K Jiang, X Yu, H Chao, L Yin… - BMC cardiovascular …, 2023 - Springer
Background Acute myocardial infarction (AMI) is a common cardiovascular disease. This
study aimed to mine biomarkers associated with AMI to aid in clinical diagnosis and …

[HTML][HTML] AKR1C3 and its transcription factor HOXB4 are promising diagnostic biomarkers for acute myocardial infarction

J Liang, Y Cao, M He, W Li, G Huang, T Ma… - Frontiers in …, 2021 - frontiersin.org
Background: A recent study disclosed that ferroptosis was an important myocyte death style
in myocardial infarction (MI). However, the diagnostic value of ferroptosis regulators and …

Identification of potential biomarkers and immune cell infiltration in acute myocardial infarction (AMI) using bioinformatics strategy

Y Xie, Y Wang, L Zhao, F Wang, J Fang - Bioengineered, 2021 - Taylor & Francis
Acute myocardial infarction (AMI) was considered a fatal disease resulting in high morbidity
and mortality; platelet activation or aggregation plays a critical role in participating in the …

Bioinformatics analyses of differentially expressed genes associated with acute myocardial infarction

Y Gao, G Qi, L Guo, Y Sun - Cardiovascular therapeutics, 2016 - Wiley Online Library
Background We aimed to predict key genes associated with acute myocardial infarction
(AMI) by bioinformatics analysis. Methods The microarray data of GSE 48060, including …